Beatriz M. A. Fontoura

Southwestern Medical Center — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

40h-index5.9kcitations84works7.62yr avg
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Research Topics

RNA Research and Splicing(47), Nuclear Structure and Function(24), RNA modifications and cancer(19), interferon and immune responses(18), RNA regulation and disease(16)

Publications84 total

Coordination of nuclear RNA processing by speckle-localized kinase TAOK2
2025Open Access
Structural mechanism of DDX39B regulation by human TREX-2 and a related complex in mRNP remodeling
Nature Communications·2025· 10 citedOpen Access
Contrasting interferon-mediated antiviral responses in human lung adenocarcinoma cells
Journal of Virology·2025Open Access
Deletion of a KSF Motif Attenuates NSP1 Host Cell Translation Shutoff and Impairs SARS-CoV-2 Virulence
2025· 1 citedOpen Access
Structures and mRNP remodeling mechanism of the TREX-2 complex
Structure·2025· 16 cited
Cellular NS1-BP protein interacts with the mRNA export receptor NXF1 to mediate nuclear export of influenza virus M mRNAs
Journal of Biological Chemistry·2024· 9 citedOpen Access
Inhibition of mRNA nuclear export promotes SARS-CoV-2 pathogenesis
Proceedings of the National Academy of Sciences·2024· 17 citedOpen Access
SARS-CoV-2 Orf6 is positioned in the nuclear pore complex by Rae1 to inhibit nucleocytoplasmic transport
Molecular Biology of the Cell·2024· 8 citedOpen Access
Impact of SARS-CoV-2 ORF6 and its variant polymorphisms on host responses and viral pathogenesis
Cell Host & Microbe·2023· 74 citedOpen Access
Structural basis for high-order complex of SARNP and DDX39B to facilitate mRNP assembly
Cell Reports·2023· 27 citedOpen Access
Influenza virus mRNAs encode determinants for nuclear export via the cellular TREX-2 complex
Nature Communications·2023· 30 citedOpen Access
Impact of SARS-CoV-2 ORF6 and its variant polymorphisms on host responses and viral pathogenesis
2022· 24 citedOpen Access
Viral–host interactions during splicing and nuclear export of influenza virus mRNAs
Current Opinion in Virology·2022· 30 citedOpen Access
Nuclear speckle integrity and function require TAO2 kinase
Proceedings of the National Academy of Sciences·2022· 11 citedOpen Access
OA01.01 Analysis of Lung Cancer Patients Receiving SARS-CoV-2 Vaccines Revealed a Minority Subset With Poor Antibody Responses Relative to Controls
Journal of Thoracic Oncology·2021· 3 citedOpen Access
Aryl Sulfonamide Inhibits Entry and Replication of Diverse Influenza Viruses via the Hemagglutinin Protein
Journal of Medicinal Chemistry·2021· 17 citedOpen Access
Abstract S01-02: Assessing vulnerability of patients with lung cancer to SARS-CoV-2 infection based on serological antibody analyses
Clinical Cancer Research·2021
Nsp1 protein of SARS-CoV-2 disrupts the mRNA export machinery to inhibit host gene expression
Science Advances·2021· 226 citedOpen Access
Viral-induced alternative splicing of host genes promotes influenza replication
eLife·2020· 73 citedOpen Access
Author response: Viral-induced alternative splicing of host genes promotes influenza replication
2020Open Access
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Frequent Co-authors

Adolfo Garcı́a-Sastre(14), Ramanavelan Sakthivel(9), Daniel R. Nussenzveig(8), Ke Zhang(6), Mary Dasso(6), Kristen W. Lynch(6), Liang Zhang(6), Agata Levay(5), David T. Levy(5), Matthew A. Esparza(5), Prasanna Bhat(5), Raquel Muñoz-Moreno(5), Neal Satterly(4), Paula A. Faria Waziry(4), Günter Blobel(4), Papia Chakraborty(4), Glen N. Barber(4), Victor Nussenzweig(4), Alexei Arnaoutov(4), Yuh Min Chook(4)