Sophie Lenoir

Inserm — France

Neuroscience · Life Sciences

13h-index1.2kcitations35works1.32yr avg
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Research Topics

Genetic Neurodegenerative Diseases(7), Protease and Inhibitor Mechanisms(6), Neonatal Respiratory Health Research(4), Pregnancy and preeclampsia studies(2), Mitochondrial Function and Pathology(2)

Publications35 total

Sex-dependent effects of intestinal epithelial TLR4 deletion induced before activity-based anorexia
2025Open Access
I004 Impact of selective lowering of mutant-Huntingtin by antisense oligonucleotides (ASOs)
2024Open Access
Mono- and Biallelic Inactivation of Huntingtin Gene in Patient-Specific Induced Pluripotent Stem Cells Reveal HTT Roles in Striatal Development and Neuronal Functions
Journal of Huntington s Disease·2024· 4 citedOpen Access
Effets de l’invalidation du TLR4 dans l’épithélium intestinal sur le métabolisme énergétique au cours de l’anorexie : focus sur la dynamique mitochondriale
Nutrition Clinique et Métabolisme·2023
Parvalbumin interneuron-derived tissue-type plasminogen activator shapes perineuronal net structure
BMC Biology·2022· 17 citedOpen Access
Pridopidine rescues BDNF/TrkB trafficking dynamics and synapse homeostasis in a Huntington disease brain-on-a-chip model
Neurobiology of Disease·2022· 37 citedOpen Access
I07 Selective lowering of mutant-huntingtin by antisense oligonucleotides (ASOs) in human cortical neurons derived from patient-specific induced pluripotent stem cells (HD-IPSC)
2022
I23 Pridopidine exerts neuroprotective effects via activation of the sigma-1 receptor
2022
A pathogenic proteolysis–resistant huntingtin isoform induced by an antisense oligonucleotide maintains huntingtin function
JCI Insight·2022· 13 citedOpen Access
I05 Increasing brain palmitoylation rescues behavior and neuropathology in huntington disease mice
2021
Increasing brain palmitoylation rescues behavior and neuropathology in Huntington disease mice
Science Advances·2021· 71 citedOpen Access
Recreating mouse cortico-hippocampal neuronal circuit in microfluidic devices to study BDNF axonal transport upon glucocorticoid treatment
STAR Protocols·2021· 12 citedOpen Access
Huntington’s disease alters human neurodevelopment
Science·2020· 314 citedOpen Access
Plasminogen Activator Inhibitor-1 (PAI-1) deficiency predisposes to depression and resistance to treatments
Acta Neuropathologica Communications·2019· 25 citedOpen Access
Post-synaptic Release of the Neuronal Tissue-Type Plasminogen Activator (tPA)
Frontiers in Cellular Neuroscience·2019· 17 citedOpen Access
Inhibition of store-operated channels by carboxyamidotriazole sensitizes ovarian carcinoma cells to anti-BclxL strategies through Mcl-1 down-regulation
Oncotarget·2018· 21 citedOpen Access
Neuronal trafficking of tissue-type plasminogen activator (tPA)
HAL (Le Centre pour la Communication Scientifique Directe)·2018Open Access
Trafic neuronal de l’activateur tissulaire du plasminogène (tPA)
ZooKeys·2018Open Access
Tissue-type plasminogen activator controls neuronal death by raising surface dynamics of extrasynaptic NMDA receptors
Cell Death and Disease·2016· 50 citedOpen Access
Impacts of tissue-type plasminogen activator (tPA) on neuronal survival
Frontiers in Cellular Neuroscience·2015· 76 citedOpen Access
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Frequent Co-authors

Frédéric Saudou(9), Denis Vivien(7), Sandrine Humbert(5), Chiara Scaramuzzino(4), Aurélie Genoux(4), Anselme L. Perrier(4), Yannick Hommet(4), Arnaud Chevilley(3), Flavie Lesept(3), Carine Ali(3), Amandine Virlogeux(3), Morgane Louessard(3), Laurent Lebouvier(3), Michel Rolland(3), Romane A Lahaye(3), Marina Cuttini(2), Monique Kaminski(2), Gesine Hansen(2), Richard de Leeuw(2), Jan Persson(2)