Chris Boutell

MRC University of Glasgow Centre for Virus Research — United Kingdom

Medicine · Health Sciences

36h-index4.7kcitations75works3.02yr avg
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Research Topics

Herpesvirus Infections and Treatments(44), interferon and immune responses(26), Ubiquitin and proteasome pathways(22), Cytomegalovirus and herpesvirus research(14), Virus-based gene therapy research(10)

Publications75 total

Interferon dependent immune memory during HSV-1 neuronal latency via increased H3K9me3 and restriction by ATRX
Nature Communications·2025Open Access
Histone H2A Ubiquitination Mediates the Establishment of Reactivation-Competent HSV-1 Latent Infection
2025Open Access
Daxx mediated histone H3.3 deposition on HSV-1 DNA restricts genome decompaction and the progression of immediate-early transcription
PLoS Pathogens·2025· 1 citedOpen Access
De novo assembly of RNA m6A modification factors into viral genome-associated nuclear bodies drives HCMV RNA accumulation
Cell Reports·2025Open Access
Interferon Dependent Immune Memory during HSV-1 Neuronal Latency Results in Increased H3K9me3 and Restriction of Reactivation by ATRX
2025· 1 citedOpen Access
Correlates of disease severity in bluetongue as a model of acute arbovirus infection
PLoS Pathogens·2024· 4 citedOpen Access
Daxx mediated histone H3.3 deposition on HSV-1 DNA restricts genome decompaction and the progression of immediate-early transcription
2024· 5 citedOpen Access
Single-genome analysis reveals a heterogeneous association of the herpes simplex virus genome with H3K27me2 and the reader PHF20L1 following infection of human fibroblasts
mBio·2024· 16 citedOpen Access
A Machine Learning Framework to Identify the Correlates of Disease Severity in Acute Arbovirus Infection
2024Open Access
Single-genome analysis reveals heterogeneous association of the Herpes Simplex Virus genome with H3K27me2 and the reader PHF20L1 following infection of human fibroblasts
2023· 2 citedOpen Access
Temperature elevation synergises with and enhances the type-I IFN-mediated restriction of MPXV
2023· 2 citedOpen Access
BTN3A3 evasion promotes the zoonotic potential of influenza A viruses
Nature·2023· 89 citedOpen Access
Superinfection exclusion creates spatially distinct influenza virus populations
PLoS Biology·2023· 39 citedOpen Access
Zoonotic avian influenza viruses evade human BTN3A3 restriction
2022· 5 citedOpen Access
PML Alternative Splice Products Differentially Regulate HAdV Productive Infection
Microbiology Spectrum·2022· 12 citedOpen Access
Superinfection exclusion creates spatially distinct influenza virus populations
2022· 6 citedOpen Access
Elevated temperature inhibits SARS-CoV-2 replication in respiratory epithelium independently of IFN-mediated innate immune defenses
PLoS Biology·2021· 46 citedOpen Access
Constitutive TRIM22 Expression in the Respiratory Tract Confers a Pre-Existing Defence Against Influenza A Virus Infection
Frontiers in Cellular and Infection Microbiology·2021· 12 citedOpen Access
PML‐NB‐dependent type I interferon memory results in a restricted form of HSV latency
EMBO Reports·2021· 37 citedOpen Access
PML-Dependent Memory of Type I Interferon Treatment Results in a Restricted Form of HSV Latency
2021Open Access
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Frequent Co-authors

Roger D. Everett(20), Anne Orr(12), Steven McFarlane(11), Matthew D. Weitzman(5), Kristen L. Conn(5), Colin Loney(5), Kyle Grant(5), Quan Gu(4), L. Tong(4), Joanna K. Wojtus(4), Delphine Cuchet-Lourenço(3), Caroline E. Lilley(3), Mira S. Chaurushiya(3), Joseph Hughes(3), Ashley P. E. Roberts(3), Rute Maria Pinto(3), Vanessa Herder(3), Edward Hutchinson(3), Sara A. Dochnal(3), Anna R. Cliffe(3)