Michael J. Currens

Frederick National Laboratory for Cancer Research — United States

Immunology and Microbiology · Life Sciences

20h-index4.7kcitations31works0.02yr avg
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Research Topics

HIV Research and Treatment(15), HIV/AIDS drug development and treatment(14), Natural Compound Pharmacology Studies(5), Carbohydrate Chemistry and Synthesis(4), Natural product bioactivities and synthesis(4)

Publications31 total

Discovery and preliminary SAR of bisbenzylisoquinoline alkaloids as inducers of C/EBPα
Bioorganic & Medicinal Chemistry·2012· 3 citedOpen Access
RSK2 Binding Models Delineate Key Features for Activity.
PubMed·2010· 2 citedOpen Access
Identification and characterization of putative Chk2 inhibitors
2007
Chemical library screen for novel inhibitors of Kaposi's sarcoma-associated herpesvirus processive DNA synthesis
Antiviral Research·2005· 36 cited
Discovery of Small-Molecule Human Immunodeficiency Virus Type 1 Entry Inhibitors That Target the gp120-Binding Domain of CD4
Journal of Virology·2005· 49 citedOpen Access
Signal Transduction and Human Disease Edited by Toren Finkel (NHLBI, NIH) and J. Silvio Gutkind (NIDCR, NIH). John Wiley and Sons, Hoboken. 2003. xviii + 470 pp. 18 × 25 cm. $100.00. ISBN 0-471-02011-7.
Journal of Natural Products·2005
Identification of HIV-1 nucleocapsid protein: nucleic acid antagonists with cellular anti-HIV activity
Biochemical and Biophysical Research Communications·2002· 54 cited
Application of High-Throughput, Molecular-Targeted Screening to Anticancer Drug Discovery
Current Topics in Medicinal Chemistry·2002· 92 cited
Analysis of the Interaction between the HIV-Inactivating Protein Cyanovirin-N and Soluble Forms of the Envelope Glycoproteins gp120 and gp41
Molecular Pharmacology·2000· 71 cited
Analysis of the Interaction between the HIV-Inactivating Protein Cyanovirin-N and Soluble Forms of the Envelope Glycoproteins gp120 and gp41
Molecular Pharmacology·2000· 2 cited
Isolation and Characterization of <i>Myrianthus holstii</i> Lectin, a Potent HIV-1 Inhibitory Protein from the Plant <i>Myrianthus holstii</i>
Journal of Natural Products·2000· 58 cited
Evolving Strategies for the Selection, Dereplication and Prioritization of Antitumor and HIV-Inhibitory Natural Products Extracts
1999· 51 cited
Discovery of cyanovirin-N, a novel human immunodeficiency virus-inactivating protein that binds viral surface envelope glycoprotein gp120: potential applications to microbicide development
Antimicrobial Agents and Chemotherapy·1997· 607 citedOpen Access
Kinetic analysis of inhibition of human immunodeficiency virus type-1 reverse transcriptase by calanolide A.
Journal of Pharmacology and Experimental Therapeutics·1996· 50 cited
Antiviral activity and mechanism of action of calanolide A against the human immunodeficiency virus type-1.
Journal of Pharmacology and Experimental Therapeutics·1996· 72 cited
HIV-Inhibitory Gallotannins from<i>Lepidobotrys staudtii</i>
Natural product letters·1996· 20 cited
Biological and biochemical anti-human immunodeficiency virus activity of UC 38, a new non-nucleoside reverse transcriptase inhibitor.
Journal of Pharmacology and Experimental Therapeutics·1996· 12 cited
A Reinvestigation of Maprounea Triterpenes
Journal of Natural Products·1995· 17 citedOpen Access
Comparative anti-HIV evaluation of diverse HIV-1-specific reverse transcriptase inhibitor-resistant virus isolates demonstrates the existence of distinct phenotypic subgroups
Antiviral Research·1995· 63 cited
Michellamine B, a novel plant alkaloid, inhibits human immunodeficiency virus-induced cell killing by at least two distinct mechanisms
Antimicrobial Agents and Chemotherapy·1995· 125 cited
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Frequent Co-authors

Michael R. Boyd(19), James B. McMahon(12), Robert H. Shoemaker(8), Dominic A. Scudiero(5), Kirk R. Gustafson(5), Robert J. Gulakowski(5), John H. Cardellina(5), Robert W. Buckheit(5), Barry R. O’Keefe(4), Yoel Kashman(4), John H. Cardellina(4), Richard W. Fuller(4), Gordon M. Cragg(3), Stephen H. Hughes(3), R W Buckheit(3), Shizuko Sei(3), Anne Monks(2), Lewis K. Pannell(2), Raymond C. Sowder(2), S H Hughes(2)