Fred A. Wright

University of North Carolina at Chapel Hill — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

76h-index41.6kcitations367works5.02yr avg
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Research Topics

Gene expression and cancer classification(55), Genetic Associations and Epidemiology(53), Genetic Mapping and Diversity in Plants and Animals(48), Genetic and phenotypic traits in livestock(36), Cystic Fibrosis Research Advances(27)

Publications357 total

Computation of Ancestry Scores with Mixed Families and Unrelated Individuals
UNC Libraries·2025Open Access
Genetic Modifiers of Cystic Fibrosis Lung Disease Severity: Whole-Genome Analysis of 7,840 Patients.
UNC Libraries·2025Open Access
Pleiotropic modifiers of age-related diabetes and neonatal intestinal obstruction in cystic fibrosis
UNC Libraries·2025Open Access
Leveraging TOPMed imputation server and constructing a cohort-specific imputation reference panel to enhance genotype imputation among cystic fibrosis patients
UNC Libraries·2025Open Access
Strain and Sex Variability in Liver, Kidney and Lung Levels of DNA Adducts EB-GII and bis-N7G-BD Following Inhalation Exposure to 1,3-Butadiene in Collaborative Cross Mice
Toxics·2025· 1 citedOpen Access
Exploring experiences of the regulatory toxicology system: system-level promoters and inhibitors of new approach methodologies
Archives of Toxicology·2025Open Access
Mediation analysis of the molecular phenotypes in a severe MASH-like liver injury mouse model
Toxicological Sciences·2025
Strain and Sex Variability in Liver, Kidney and Lung Levels of DNA Adducts EB-GII and <em>bis</em>-N7G-BD Following Inhalation Exposure to 1,3-Butadiene in Collaborative Cross Mice
Preprints.org·2025Open Access
Application of Ion Mobility Spectrometry–Mass Spectrometry for Compositional Characterization and Fingerprinting of a Library of Diverse Crude Oil Samples
UNC Libraries·2025Open Access
Signature gene expression model for quantitative evaluation of MASH-like liver injury in mice
Toxicology and Applied Pharmacology·2025· 1 cited
HAP-SAMPLE2: data-based resampling for association studies with admixture
Bioinformatics·2025Open Access
An approach to uncover significant direct and mediated relationships in multi-dimensional new approach methods (NAMs) data: A case study of hazard evaluation of petroleum UVCBs
The Science of The Total Environment·2025· 1 citedOpen Access
Genetic effects on chromatin accessibility uncover mechanisms of liver gene regulation and quantitative traits
Genome Research·2025· 4 citedOpen Access
MagicalRsq: Machine-learning-based genotype imputation quality calibration
UNC Libraries·2025Open Access
Congenital Langerhans Cell Histiocytosis With Novel <i>KCL1::RAF1</i> Gene Fusion Identified Through Routine Whole‐Genome Sequencing
Pediatric Blood & Cancer·2025
A workflow for human health hazard evaluation using transcriptomic data and Key Characteristics-based gene sets
Toxicological Sciences·2025· 2 cited
Asian diversity in human immune cells
Cell·2025· 37 citedOpen Access
Liver eQTL meta-analysis illuminates potential molecular mechanisms of cardiometabolic traits
UNC Libraries·2025Open Access
Examining risk assessment implications of genetic and dose-dependent dynamics of lead exposure in breastfeeding using the collaborative cross mouse population
Toxicological Sciences·2025Open Access
Zebrafish Cyp1b1 knockout alters eye and brain metabolomic profiles, affecting ocular and neurobehavioral function
Toxicology and Applied Pharmacology·2025Open Access
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Frequent Co-authors

Ayellet V. Segrè(10), Daniel G. MacArthur(10), Andrew B. Nobel(10), Tuuli Lappalainen(10), Emmanouil T. Dermitzakis(10), Gad Getz(10), Ivan Rusyn(9), Ferrán Reverter(9), Roderic Guigó(9), Eric R. Gamazon(9), Nancy J. Cox(9), Xiaoquan Wen(9), Kristin Ardlie(9), Pedro G. Ferreira(8), Marta Melé(8), Alexis Battle(8), Hae Kyung Im(7), Liqun Qi(7), Manolis Kellis(7), Patrick F. Sullivan(7)