Gurdyal S. Besra

University of Birmingham — United Kingdom

Medicine · Health Sciences

113h-index42.5kcitations673works3.32yr avg
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Research Topics

Tuberculosis Research and Epidemiology(250), Immune Cell Function and Interaction(228), Mycobacterium research and diagnosis(185), T-cell and B-cell Immunology(129), Biochemical and Molecular Research(110)

Publications673 total

Developing pyrazole–oxadiazole conjugates as potent anti-tubercular agents: an <i>in silico</i> and <i>in vitro</i> approach
RSC Medicinal Chemistry·2025Open Access
Relating corynebacterial cell envelope layers to its biochemical and physical properties
The Cell Surface·2025· 1 citedOpen Access
The deacetylase NagA mediates the remodeling and recycling of peptidoglycan-derived amino sugars in mycobacteria
Journal of Biological Chemistry·2025· 1 citedOpen Access
Relating corynebacterial cell envelope layers to its biochemical and physical properties
SSRN Electronic Journal·2025Open Access
Cryo-electron microscopy structure of the di-domain core of Mycobacterium tuberculosis polyketide synthase 13, essential for mycobacterial mycolic acid synthesis
Microbiology·2024· 2 citedOpen Access
Exploration of vanoxerine analogues as antibacterial agents
The Journal of Antibiotics·2024Open Access
Conserved allomorphs of MR1 drive the specificity of MR1-restricted TCRs
Frontiers in Oncology·2024· 9 citedOpen Access
Novel hybrids of 1,2,3-triazole-benzoxazole: design, synthesis, and assessment of DprE1 enzyme inhibitors using fluorometric assay and computational analysis
Journal of Enzyme Inhibition and Medicinal Chemistry·2024· 8 citedOpen Access
Author Correction: The mycobacterial glycoside hydrolase LamH enables capsular arabinomannan release and stimulates growth
Nature Communications·2024Open Access
The mycobacterial glycoside hydrolase LamH enables capsular arabinomannan release and stimulates growth
Nature Communications·2024· 9 citedOpen Access
A structural perspective of how T cell receptors recognize the CD1 family of lipid antigen–presenting molecules
Journal of Biological Chemistry·2024· 9 citedOpen Access
CryoEM structure of the di-domain core of <i>Mycobacterium tuberculosis</i> polyketide synthase 13, essential for mycobacterial mycolic acid synthesis
2024Open Access
Structural analysis of phosphoribosyltransferase-mediated cell wall precursor synthesis in Mycobacterium tuberculosis
Nature Microbiology·2024· 8 citedOpen Access
Top five unanswered questions in bacterial cell wall research
The Cell Surface·2024· 3 citedOpen Access
Novel Hybrids of 1,2,3-Triazole-Benzoxazole: Design, Synthesis, and Assessment of Dpre1 Enzyme Inhibitors Using Fluorometric Assay and Computational Analysis
SSRN Electronic Journal·2024Open Access
Professor David Minnikin Memorial Lecture: An era of the mycobacterial cell wall lipid biomarkers
Tuberculosis·2023Open Access
Sensitive lipid biomarker detection for tuberculosis in late Neanderthal skeletons from Subalyuk Cave, Hungary
Tuberculosis·2023· 5 citedOpen Access
362 Allelic variants of MR1 drive cancer and allo-reactivity by MR1-restricted T cells
Regular and Young Investigator Award Abstracts·2023Open Access
The mycobacterial glycoside hydrolase LamH enables capsular arabinomannan release and stimulates growth
2023· 1 citedOpen Access
Conserved allomorphs of MR1 drive specificity of MR1-restricted TCRs
2023· 2 citedOpen Access
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Frequent Co-authors

Michael B. Brenner(7), Petr A. Illarionov(7), William R. Jacobs(7), Steven A. Porcelli(6), Patrick J. Brennan(5), Laurent Kremer(5), Vincenzo Cerundolo(5), Elizabeth A. Leadbetter(5), David E. Minnikin(4), Manfred Brigl(4), Lynn G. Dover(4), Dale I. Godfrey(3), Katarı́na Mikus̃ová(3), D. Branch Moody(3), Sudagar S. Gurcha(3), Patrick J. Brennan(3), Mariolina Salio(3), Natacha Veerapen(3), Facundo D. Batista(3), John T. Belisle(2)