Sudagar S. Gurcha

University of Birmingham — United Kingdom

Medicine · Health Sciences

37h-index4.3kcitations70works5.72yr avg
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Research Topics

Tuberculosis Research and Epidemiology(29), Carbohydrate Chemistry and Synthesis(28), Mycobacterium research and diagnosis(24), Biochemical and Molecular Research(23), Glycosylation and Glycoproteins Research(19)

Publications70 total

Author Correction: The mycobacterial glycoside hydrolase LamH enables capsular arabinomannan release and stimulates growth
Nature Communications·2024Open Access
The mycobacterial glycoside hydrolase LamH enables capsular arabinomannan release and stimulates growth
Nature Communications·2024· 9 citedOpen Access
Structural analysis of phosphoribosyltransferase-mediated cell wall precursor synthesis in Mycobacterium tuberculosis
Nature Microbiology·2024· 8 citedOpen Access
The mycobacterial glycoside hydrolase LamH enables capsular arabinomannan release and stimulates growth
2023· 1 citedOpen Access
DprE2 is a molecular target of the anti-tubercular nitroimidazole compounds pretomanid and delamanid
Nature Communications·2023· 38 citedOpen Access
Structure of the priming arabinosyltransferase AftA required for AG biosynthesis of<i>Mycobacterium tuberculosis</i>
Proceedings of the National Academy of Sciences·2023· 16 citedOpen Access
NSC19723, a Thiacetazone-Like Benzaldehyde Thiosemicarbazone Improves the Efficacy of TB Drugs <i>In Vitro</i> and <i>In Vivo</i>
Microbiology Spectrum·2022· 7 citedOpen Access
Cord Factor and Peptidoglycan Recapitulate the Th17-Promoting Adjuvant Activity of Mycobacteria through Mincle/CARD9 Signaling and the Inflammasome
UNC Libraries·2020Open Access
Cryo-EM snapshots of mycobacterial arabinosyltransferase complex EmbB2-AcpM2
Protein & Cell·2020· 22 citedOpen Access
Structures of cell wall arabinosyltransferases with the anti-tuberculosis drug ethambutol
Science·2020· 162 citedOpen Access
The singular Corynebacterium glutamicum Emb arabinofuranosyltransferase polymerises the α(1 → 5) arabinan backbone in the early stages of cell wall arabinan biosynthesis
The Cell Surface·2018· 16 citedOpen Access
Fluorescent mannosides serve as acceptor substrates for glycosyltransferase and sugar-1-phosphate transferase activities in Euglena gracilis membranes
Carbohydrate Research·2016· 21 citedOpen Access
Identification of KasA as the cellular target of an anti-tubercular scaffold
Nature Communications·2016· 96 citedOpen Access
THPP target assignment reveals EchA6 as an essential fatty acid shuttle in mycobacteria
Nature Microbiology·2016· 68 citedOpen Access
Biochemical and Structural Characterization of Mycobacterial Aspartyl-tRNA Synthetase AspS, a Promising TB Drug Target
PLoS ONE·2014· 35 citedOpen Access
Selectfluor and NFSI <i>exo</i>‐Glycal Fluorination Strategies Applied to the Enhancement of the Binding Affinity of Galactofuranosyltransferase Gl<i>f</i>T2 Inhibitors
Chemistry - A European Journal·2014· 27 cited
Keto-Mycolic Acid-Dependent Pellicle Formation Confers Tolerance to Drug-Sensitive Mycobacterium tuberculosis
mBio·2013· 134 citedOpen Access
Cord Factor and Peptidoglycan Recapitulate the Th17-Promoting Adjuvant Activity of Mycobacteria through Mincle/CARD9 Signaling and the Inflammasome
The Journal of Immunology·2013· 134 citedOpen Access
Ppm1-Encoded Polyprenyl Monophosphomannose Synthase Activity Is Essential for Lipoglycan Synthesis and Survival in Mycobacteria
PLoS ONE·2012· 30 citedOpen Access
Identification of Novel Mt-Guab2 Inhibitor Series Active against M. tuberculosis
PLoS ONE·2012· 27 citedOpen Access
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Frequent Co-authors

Gurdyal S. Besra(50), Robert C. Reynolds(9), Laurent Kremer(8), Ashish K. Pathak(6), Apoorva Bhatt(5), Vibha Pathak(5), William R. Jacobs(4), Natacha Veerapen(4), Alain R. Baulard(4), Katherine A. Abrahams(4), Paul G. Hitchen(4), Howard R. Morris(4), Anne Dell(4), William J. Suling(4), Steven A. Porcelli(3), Sarah M. Batt(3), Jérôme Nigou(3), Todd L. Lowary(3), Christina M. J. E. Vandenbroucke‐Grauls(3), Camille Locht(3)