Sigrid A. Langhans

Nemours Children's Health System — United States

Medicine · Health Sciences

18h-index3.0kcitations59works3.12yr avg
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Research Topics

Glioma Diagnosis and Treatment(8), Epigenetics and DNA Methylation(8), Cancer Cells and Metastasis(8), 3D Printing in Biomedical Research(7), Hydrogels: synthesis, properties, applications(6)

Publications59 total

Advances in Molecular Imaging of VEGFRs: Innovations in Imaging and Therapeutics
International Journal of Molecular Sciences·2025· 3 citedOpen Access
Brain Organoids and Assembloids—From Disease Modeling to Drug Discovery
Cells·2025· 7 citedOpen Access
YAP/TAZ-associated cell signaling – at the crossroads of cancer and neurodevelopmental disorders
Frontiers in Cell and Developmental Biology·2025· 6 citedOpen Access
Tryptophan Kynurenine Pathway-Based Imaging Agents for Brain Disorders and Oncology—From Bench to Bedside
Biomolecules·2025· 2 citedOpen Access
Radiotracers for Molecular Imaging of Angiotensin-Converting Enzyme 2
International Journal of Molecular Sciences·2024· 3 citedOpen Access
MDB-35. DEVELOPMENT OF DUAL LUCIFERASE ASSAY FOR 3D-COMPATIBLE HIGH THROUGHPUT SCREENING IN MEDULLOBLASTOMA
Neuro-Oncology·2024Open Access
PET Imaging of Neurofibromatosis Type 1 with a Fluorine-18 Labeled Tryptophan Radiotracer
Pharmaceuticals·2024· 1 citedOpen Access
Rational design and synthesis of angiotensin-converting enzyme 2 inhibitors targeting severe acute respiratory syndrome coronavirus 2
Physiology·2023· 1 cited
Abusive Head Trauma Animal Models: Focus on Biomarkers
International Journal of Molecular Sciences·2023· 6 citedOpen Access
3D Hydrogel Cultures for High-Throughput Drug Discovery
Methods in molecular biology·2023· 3 citedOpen Access
Advanced Neuroimaging Approaches to Pediatric Brain Tumors
Cancers·2022· 33 citedOpen Access
Radiosynthesis of 1-(2-[<sup>18</sup>F]Fluoroethyl)-L-Tryptophan using a One-pot, Two-step Protocol
Journal of Visualized Experiments·2021
Radiosynthesis of 1-(2-[<sup>18</sup>F]Fluoroethyl)-L-Tryptophan using a One-pot, Two-step Protocol
Journal of Visualized Experiments·2021· 4 cited
Unravelling neuroinflammation in abusive head trauma with radiotracer imaging
Pediatric Radiology·2021· 7 cited
Using 3D in vitro cell culture models in anti-cancer drug discovery
Expert Opinion on Drug Discovery·2021· 31 cited
In Vivo and Ex Vivo Pediatric Brain Tumor Models: An Overview
Frontiers in Oncology·2021· 33 citedOpen Access
Abstract 1652: Tumor-specific PET imaging with an 18F-labeled tryptophan analogue in a transgenic medulloblastoma mouse model
Cancer Research·2020
Preliminary evaluation of shaken baby syndrome using [18F]GE180
2020
PET imaging of medulloblastoma with an 18F-labeled tryptophan analogue in a transgenic mouse model
Scientific Reports·2020· 12 citedOpen Access
Moving Myeloid Leukemia Drug Discovery Into the Third Dimension
Frontiers in Pediatrics·2019· 15 citedOpen Access
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Frequent Co-authors

Xuyi Yue(15), Darrin J. Pochan(11), Alisa Litan(9), Vinay Kandula(9), Lauren W. Averill(9), Rahul Nikam(8), Heidi H. Kecskemethy(8), Seung Joon Lee(7), Peter Worthington(6), Zhiqin Li(6), Stephan Lindsey(5), Sonali P. Barwe(5), Zhiqin Li(5), Yangchun Xin(5), Arabinda K. Choudhary(4), Shaohui Zhang(4), Wenqi Xu(4), Erik Stauff(4), Joel P. Schneider(3), Jessie Sun(3)