Stephan Lindsey

Alfred I. duPont Hospital for Children — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

14h-index893citations29works0.02yr avg
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Research Topics

Protein Tyrosine Phosphatases(6), Platelet Disorders and Treatments(5), Cytokine Signaling Pathways and Interactions(5), Epigenetics and DNA Methylation(3), Acute Myeloid Leukemia Research(3)

Publications29 total

Na,K-ATPase β1-subunit is a target of sonic hedgehog signaling and enhances medulloblastoma tumorigenicity
Molecular Cancer·2015· 13 citedOpen Access
Beta Hairpin Peptide Hydrogels as an Injectable Solid Vehicle for Neurotrophic Growth Factor Delivery
Biomacromolecules·2015· 86 citedOpen Access
Crosstalk of Oncogenic Signaling Pathways during Epithelial–Mesenchymal Transition
Frontiers in Oncology·2014· 157 citedOpen Access
Epidermal Growth Factor Signaling in Transformed Cells
International review of cell and molecular biology·2014· 119 citedOpen Access
Thrombocytosis
2013
Sonic Hedgehog-Induced Histone Deacetylase Activation Is Required for Cerebellar Granule Precursor Hyperplasia in Medulloblastoma
PLoS ONE·2013· 49 citedOpen Access
The Bleeding Defect Exhibited by Aryl Hydrocarbon Receptor-Null Mice Is Due to Defective Collagen-Dependent Outside-in Signaling
Blood·2012
The Evolving Role of the Aryl Hydrocarbon Receptor (AHR) in the Normophysiology of Hematopoiesis
Stem Cell Reviews and Reports·2012· 75 citedOpen Access
Proposed megakaryocytic regulon of p53: the genes engaged to control cell cycle and apoptosis during megakaryocytic differentiation
Physiological Genomics·2012· 33 citedOpen Access
The Importance of Physiologically Inspired Physicochemical Parameters on Hematopoietic Stem-Cell Maintenance and Lineage-Specific Differentiation in <i>Ex Vivo</i> Cultures
WORLD SCIENTIFIC eBooks·2011· 1 cited
The Aryl Hydrocarbon Receptor Influences Multiple Stages of Megakaryocyte Differentiation
Blood·2011
The aryl hydrocarbon receptor (AHR) transcription factor regulates megakaryocytic polyploidization
British Journal of Haematology·2011· 41 citedOpen Access
Hes1 Expression Impacts Megakaryocytic Polyploidization and May Contribute to the Platelet Defects Found In Aryl Hydrocarbon Receptor (AhR)-Null Mice.
Blood·2010
Thrombopoietin Stimulation Leads to Enhanced Polyploidization in p53-/- Bone Marrow Megakaryocytes: In Vivo and in Vitro Studies.
Blood·2009
In Megakaryocytic Differentiation, the Aryl Hydrocarbon Receptor (AhR) Transcription Factor Regulates Hes1 Expression and Megakaryocytic Polyploidization.
Blood·2009
Mechanistic studies on the effects of nicotinamide on megakaryocytic polyploidization and the roles of NAD+ levels and SIRT inhibition
Experimental Hematology·2009· 45 cited
Constitutively Active SHP2 Cooperates with HoxA10 Overexpression to Induce Acute Myeloid Leukemia
Journal of Biological Chemistry·2008· 51 citedOpen Access
Tumor Suppressor Protein p53 Affects Megakaryocytic Maturation: In Vivo and Ex Vivo Post-Translational Modification Studies
Blood·2008· 1 cited
Constitutive Activation of SHP2 Protein Tyrosine Phosphatase Cooperates with HoxA10 Overexpression for Progression to Acute Myeloid Leukemia in a Murine Model
Blood·2008
Nicotinamide Increases the Megakaryocytic Maturation of Human Hematopoietic Stem Cells Primarily Due to SIRT Inhibition
Blood·2008· 1 cited
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Frequent Co-authors

Eleftherios T. Papoutsakis(13), Elizabeth A. Eklund(9), Pani A. Apostolidis(7), William M. Miller(7), Sigrid A. Langhans(5), Elizabeth Horvath(5), Weiqi Huang(5), Chunliu Zhu(4), Hao Wang(3), Gurveen Saberwal(3), Ling Bei(3), Iwona Konieczna(2), Seung Joon Lee(2), Bruce Graves(2), Lisa M. Giammona(2), Swapna Panuganti(2), Jan M. Kemper(2), Peter G. Fuhrken(2), Anne Duchoud(2), Joseph H. Piatt(1)