Simone A. Joosten

Leiden University Medical Center — Netherlands

Medicine · Health Sciences

52h-index7.7kcitations174works2.62yr avg
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Research Topics

Tuberculosis Research and Epidemiology(73), Mycobacterium research and diagnosis(39), Immune Cell Function and Interaction(37), T-cell and B-cell Immunology(29), Immune responses and vaccinations(20)

Publications172 total

Antibodies in tuberculosis: functional capacity as key determinant
Infection and Immunity·2026Open Access
Prior Exposure of Airway Epithelial Cells to Mycobacteria Reduces Subsequent Mycobacterium tuberculosis Infection and Resulting Inflammation
Journal of Innate Immunity·2025Open Access
Differential diagnosis of sarcoidosis and tuberculosis using Mycobacterium tuberculosis-specific blood immune signatures 3700
The Journal of Immunology·2025Open Access
Circulating metabolites associated with protection against Mycobacterium tuberculosis infection and inhibition of mycobacterial growth
2025Open Access
<i>Mycobacterium tuberculosis</i> –specific blood immune signatures distinguish sarcoidosis from tuberculosis disease
The Journal of Immunology·2025Open Access
Conformation of HLA-E/peptide complex guides interaction with two novel HLA-E receptors: Stabilin 1 and 2
PLoS ONE·2025Open Access
Correlation of C-Reactive Protein With Severe Fatigue in Patients With Myasthenia Gravis
Neurology Neuroimmunology & Neuroinflammation·2025· 1 citedOpen Access
NK cell-macrophage interactions in granulomas correlate with limited tuberculosis pathology
PLoS Pathogens·2025· 1 citedOpen Access
Protocol to infect differentiated human primary bronchial epithelial cells with live mycobacteria and determine intracellular load
STAR Protocols·2025· 1 citedOpen Access
Protocol for development, visualization, and quantification of mycobacterial biofilms on primary human airway epithelial cells
STAR Protocols·2025Open Access
Individual- and population-associated heterogeneity in vaccine-induced immune responses. The impact of inflammatory status and diabetic comorbidity
Seminars in Immunology·2025· 6 citedOpen Access
Sera contributing to mycobacterial growth restriction in vitro display enhanced Fc-mediated phagocytosis
iScience·2025· 2 citedOpen Access
HLA-E/peptide complexes differentially interact with NKG2A/CD94 and T cell receptors
The Journal of Immunology·2025· 6 citedOpen Access
NK cell-macrophage interactions in granulomas correlate with limited tuberculosis pathology
2025Open Access
HLA-E/Mtb specific CD4+ and CD8+ T cells have a memory phenotype in individuals with TB infection
Frontiers in Immunology·2024· 1 citedOpen Access
Mtb-Specific HLA-E-Restricted T Cells Are Induced during Mtb Infection but Not after BCG Administration in Non-Human Primates and Humans
Vaccines·2024· 2 citedOpen Access
Mycobacteria develop biofilms on airway epithelial cells and promote mucosal barrier disruption
iScience·2024· 17 citedOpen Access
<i>Mtb</i> specific HLA-E restricted T cells are induced during <i>Mtb</i> infection but not after BCG administration in non-human primates and humans
2024· 1 citedOpen Access
Longitudinal soluble marker profiles reveal strong association between cytokine storms resulting from macrophage activation and disease severity in COVID-19 disease
Scientific Reports·2024· 4 citedOpen Access
Longitudinal soluble marker profiles reveal strong association between cytokine storms resulting from macrophage activation and disease severity in COVID-19 disease
2024Open Access
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Frequent Co-authors

Tom H. M. Ottenhoff(39), Krista E. van Meijgaarden(13), Gerhard Walzl(12), Hazel M. Dockrell(9), Annemieke Geluk(9), Thomas J. Scriba(8), Stefan H. E. Kaufmann(8), Mariëlle C. Haks(7), January Weiner(6), Steven G. Smith(6), E. Jane Hughes(6), Gian van der Spuy(6), Willem A. Hanekom(6), Léanie Kleynhans(6), Michèl R. Klein(6), Nicole Bilek(6), Cees van Kooten(6), Lorna Paul(6), Nadia Caccamo(5), Francesco Dieli(5)