Diana Wetmore

Alzheimer's Drug Discovery Foundation — United States

Medicine · Health Sciences

15h-index1.6kcitations36works0.02yr avg
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Research Topics

Cystic Fibrosis Research Advances(13), Neonatal Respiratory Health Research(5), Enzyme Production and Characterization(5), Advanced biosensing and bioanalysis techniques(4), Legume Nitrogen Fixing Symbiosis(4)

Publications36 total

Mechanism of dual pharmacological correction and potentiation of human CFTR
2022· 15 citedOpen Access
Semi-Mechanistic Pharmacokinetic-Pharmacodynamic Model of Camostat Mesylate-Predicted Efficacy against SARS-CoV-2 in COVID-19
Microbiology Spectrum·2022· 7 citedOpen Access
The Harrington Discovery Institute and Alzheimer’s Disease Drug Development
Cambridge University Press eBooks·2022
Targeted Proteomic Quantitation of the Absolute Expression and Turnover of Cystic Fibrosis Transmembrane Conductance Regulator in the Apical Plasma Membrane
Figshare·2020Open Access
Faculty Opinions recommendation of Combining autophagy stimulators and cellulose ethers for therapy against prion disease.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2019
Faculty Opinions recommendation of Advances in lead generation.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2019
Faculty Opinions recommendation of Eradication of Triple-Negative Breast Cancer Cells by Targeting Glycosylated PD-L1.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2018Open Access
Faculty Opinions recommendation of The Hsp70 interdomain linker is a dynamic switch that enables allosteric communication between two structured domains.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2017
Faculty Opinions recommendation of Common pitfalls in preclinical cancer target validation.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2017
Faculty Opinions recommendation of Large-Scale Analysis of Hydrogen Bond Interaction Patterns in Protein-Ligand Interfaces.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2017
Faculty Opinions recommendation of Histone deacetylase 6 structure and molecular basis of catalysis and inhibition.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2016
Faculty Opinions recommendation of Crystal structure of a DNA catalyst.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2016
Faculty Opinions recommendation of Antimicrobial interactions: mechanisms and implications for drug discovery and resistance evolution.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2015
Structural basis for RNA replication by the hepatitis C virus polymerase
Science·2015· 345 cited
Targeted Proteomic Quantitation of the Absolute Expression and Turnover of Cystic Fibrosis Transmembrane Conductance Regulator in the Apical Plasma Membrane
Journal of Proteome Research·2014· 15 citedOpen Access
Serum metabolomics indicate altered cellular energy metabolism in children with cystic fibrosis
Pediatric Pulmonology·2013· 40 cited
Interactions between an inflammatory response to infection and protein trafficking pathways favor correction of defective protein trafficking in Cystic Fibrosis
Bioinformation·2010· 1 citedOpen Access
Small molecule correctors of F508del-CFTR discovered by structure-based virtual screening
Journal of Computer-Aided Molecular Design·2010· 87 citedOpen Access
Integrated biophysical studies implicate partial unfolding of NBD1 of CFTR in the molecular pathogenesis of F508del cystic fibrosis
Protein Science·2010· 103 citedOpen Access
Thermal unfolding studies show the disease causing F508del mutation in CFTR thermodynamically destabilizes nucleotide‐binding domain 1
Protein Science·2010· 133 citedOpen Access
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Frequent Co-authors

Rodney S. Roche(6), J.F. Hunt(5), Christie G. Brouillette(4), Elizabeth Joseloff(4), Irina I. Protasevich(3), Zhengrong Yang(3), S. Atwell(3), Xun Zhao(3), Sui‐Lam Wong(3), Penelope W. Codding(3), Spencer Emtage(2), H.A. Lewis(2), K. Conners(2), Frances Lu(2), William B. Guggino(2), Kay A. Lawton(2), Michael V. Milburn(2), John Ryals(2), Lining Guo(2), Melissa A. Ashlock(2)