James A. Ferrendelli

Neuroscience · Life Sciences

49h-index7.8kcitations165works0.02yr avg
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Research Topics

Neuroscience and Neuropharmacology Research(68), Epilepsy research and treatment(39), Pharmacological Effects and Toxicity Studies(29), Retinal Development and Disorders(19), Ion channel regulation and function(14)

Publications165 total

What You See Is Not What You Get
Archives of Neurology·2007· 1 cited
Levetiracetam Noninferior to Carbamazepine for Newly Diagnosed Epilepsy
Journal watch·2007
Diagnosis and treatment selection in elderly patients with epilepsy
2006· 4 cited
Enantioselectivity of α-Benzyl-α-methyl-γ-butyrolactone-Mediated Modulation of Anticonvulsant Activity and GABAA Receptor Function
Journal of Pharmacology and Experimental Therapeutics·2004· 14 cited
Use of levetiracetam in a population of patients aged 65 years and older: a subset analysis of the KEEPER trial*1
Epilepsy & Behavior·2003· 6 cited
Use of levetiracetam in a population of patients aged 65 years and older: a subset analysis of the KEEPER trial
Epilepsy & Behavior·2003· 85 cited
Corrigendum to “The KEEPER™ trial: levetiracetam adjunctive treatment of partial-onset seizures in an open-label community-based study” [Epilepsy Res. 54 (2003) 153–162]
Epilepsy Research·2003· 6 cited
The KEEPER™ trial: levetiracetam adjunctive treatment of partial-onset seizures in an open-label community-based study
Epilepsy Research·2003· 98 cited
Concerns with Antiepileptic Drug Initiation: Safety, Tolerability, and Efficacy
Epilepsia·2001· 34 cited
Concerns with Antiepileptic Drug Initiation: Safety, Tolerability, and Efficacy
Epilepsia·2001· 13 cited
Pharmacology of Antiepileptic Drug Polypharmacy
Epilepsia·1999· 8 cited
Structure-activity studies of fluoroaljyl-substituted γ-butyrolactone and γ-thiobutyrolactone modulators of GABAA receptor function
Bioorganic & Medicinal Chemistry·1998· 28 cited
Lactone Modulation of the γ-Aminobutyric Acid A Receptor: Evidence for a Positive Modulatory Site
Molecular Pharmacology·1997· 34 cited
ChemInform Abstract: Synthesis and Anticonvulsant Activities of 3,3‐Dialkyl‐ and 3‐Alkyl‐3‐ benzyl‐2‐piperidinones (δ‐Valerolactams) and Hexahydro‐2H‐azepin‐ 2‐ones (.epsilon.‐Caprolactams).
ChemInform·1997
Voltage-Dependent Calcium Channels as Targets for Convulsant and Anticonvulsant Alkyl-Substituted Thiobutyrolactones
Journal of Pharmacology and Experimental Therapeutics·1997· 15 cited
Synthesis and Anticonvulsant Activities of 3,3-Dialkyl- and 3-Alkyl-3-benzyl-2-piperidinones (δ-Valerolactams) and Hexahydro-2<i>H</i>-azepin-2-ones (ε-Caprolactams)
Journal of Medicinal Chemistry·1997· 44 cited
ChemInform Abstract: 3,3‐Dialkyl‐ and 3‐Alkyl‐3‐benzyl‐Substituted 2‐Pyrrolidinones: A New Class of Anticonvulsant Agents.
ChemInform·1996
Physiological comparison of α-ethyl-α-methyl-γ-thiobutyrolactone with benzodiazepine and barbiturate modulators of GABAA receptors
Neuropharmacology·1996· 16 cited
3,3-Dialkyl- and 3-Alkyl-3-Benzyl-Substituted 2-Pyrrolidinones:  A New Class of Anticonvulsant Agents
Journal of Medicinal Chemistry·1996· 88 cited
Use of rational polypharmacy to treat epilepsy.
PubMed·1996· 3 cited
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Frequent Co-authors

Dorothy A. Kinscherf(7), Marek A. Mirski(4), John W. Miller(4), Douglas F. Covey(4), Mark S. Minkes(3), Ming-Jui Chang(3), David Kipnis(3), Adolph I. Cohen(3), Isabelle A. Hall(3), Ann C. McKeon(3), Katherine D. Holland(3), Eugene H. Rubin(3), Philip Needleman(2), Alton L. Steiner(2), O. H. Lowry(2), Edward W. Troyer(2), A. Blank(2), Martha J. Morrell(2), Ilo E. Leppik(2), Jacqueline A. French(2)