David Sebastián

Royal College of Nursing — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

35h-index8.1kcitations92works2.52yr avg
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Research Topics

Mitochondrial Function and Pathology(32), Adipose Tissue and Metabolism(29), Autophagy in Disease and Therapy(17), ATP Synthase and ATPases Research(12), Metabolism and Genetic Disorders(11)

Publications91 total

Identification of Neuritin 1 as a local metabolic regulator of brown adipose tissue
Nature Communications·2025Open Access
A Correlational Study to Assess the Degree of Lifestyle Modifications and its Relationship with Quality of Life among patients undergoing Hemodialysis in a Tertiary Care Hospital in Central Kerala
International Journal of Advances in Nursing Management·2025
Fasting‐Induced Hepatic Gluconeogenesis Is Compromised In <i>Anxa6</i> <sup> <i>−/−</i> </sup> Mice
Journal of Cellular Physiology·2025Open Access
Ablation of LAT2 Transporter Causes Intramuscular Glutamine Accumulation and Inhibition of Fasting‐Induced Proteolysis
Journal of Cachexia Sarcopenia and Muscle·2025· 2 citedOpen Access
Abstract 1055 Palmitate-induced lipotoxicity in muscle cells: The role of lysosomal stress and mitophagy deficiency
Journal of Biological Chemistry·2025Open Access
Defective Slc7a7 transport reduces erythropoietin compromising erythropoiesis
Molecular Medicine·2025· 2 citedOpen Access
Fasting-induced hepatic gluconeogenesis is compromised in <i> Anxa6 <sup>−/−</sup> </i> mice
2025Open Access
BNIP3 Downregulation Ameliorates Muscle Atrophy in Cancer Cachexia
Cancers·2024· 6 citedOpen Access
Neuregulin 4 Downregulation Alters Mitochondrial Morphology and Induces Oxidative Stress in 3T3-L1 Adipocytes
International Journal of Molecular Sciences·2024· 4 citedOpen Access
MITOCHONDRIAL FITNESS SUSTAINS HEALTHY MUSCLE AGING
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease·2024
THU-209 Effect of inhibition of the protein tyrosine phosphatase 1B in liver progenitor cells under an steatohepatitis environment in mice
Journal of Hepatology·2024
TP53INP2-dependent activation of muscle autophagy ameliorates sarcopenia and promotes healthy aging
Autophagy·2024· 18 citedOpen Access
Age‐related muscle atrophy? Mitofusin 2 the rescue
Acta Physiologica·2024· 1 citedOpen Access
Mitofusin-2 induced by exercise modifies lipid droplet-mitochondria communication, promoting fatty acid oxidation in male mice with NAFLD
Metabolism·2023· 37 cited
<i>Cpt1a</i> silencing in <scp>AgRP</scp> neurons improves cognitive and physical capacity and promotes healthy aging in male mice
Aging Cell·2023· 4 citedOpen Access
Mitochondrial fitness sustains healthy muscle aging
Aging·2023· 1 citedOpen Access
Splice variants of mitofusin 2 shape the endoplasmic reticulum and tether it to mitochondria
Science·2023· 129 cited
Coordination of mitochondrial and lysosomal homeostasis mitigates inflammation and muscle atrophy during aging
Free Radical Biology and Medicine·2023
Disruption of mitochondrial dynamics triggers muscle inflammation through interorganellar contacts and mitochondrial DNA mislocation
Nature Communications·2023· 82 citedOpen Access
Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction‐associated fatty liver disease
Hepatology·2022· 25 citedOpen Access
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Frequent Co-authors

António Zorzano(40), Manuel Palacı́n(15), María Isabel Hernández‐Álvarez(11), Dolors Serra(9), Juan Pablo Muñoz(8), Laura Herrero(8), David Sala(6), Jessica Segalés(5), Fausto G. Hegardt(5), Guillermina Asins(5), Marc Liesa(4), Saška Ivanova(4), Andrea Irazoki(4), Eleonora Sorianello(3), Paula Martínez-Cristóbal(3), Manuel Noguera(3), Angels Díaz‐Ramos(3), Caroline Mauvezin(3), Evarist Planet(3), Natàlia Plana(3)