Guillermina Asins

Institut de Biomedicina de la Universitat de Barcelona

Biochemistry, Genetics and Molecular Biology · Life Sciences

26h-index2.0kcitations59works0.02yr avg
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Research Topics

Metabolism and Genetic Disorders(38), Peroxisome Proliferator-Activated Receptors(21), Mitochondrial Function and Pathology(19), Diet and metabolism studies(7), Pancreatic function and diabetes(6)

Publications59 total

(−)-UB006: A new fatty acid synthase inhibitor and cytotoxic agent without anorexic side effects
European Journal of Medicinal Chemistry·2017· 18 citedOpen Access
Long-Term Increased Carnitine Palmitoyltransferase 1A Expression in Ventromedial Hypotalamus Causes Hyperphagia and Alters the Hypothalamic Lipidomic Profile
PLoS ONE·2014· 42 citedOpen Access
Differential Pharmacologic Properties of the Two C75 Enantiomers: (+)‐C75 Is a Strong Anorectic Drug; (−)‐C75 Has Antitumor Activity
Chirality·2013· 36 citedOpen Access
Convenient synthesis of C75, an inhibitor of FAS and CPT1
RSC Advances·2013· 3 cited
Methodological concerns about a recent meta-analysis of the influence of the I148M variant of patatin-like phospholipase domain containing 3 on the susceptibility and histological severity of nonalcoholic fatty liver disease
Hepatology·2011
Molecular Therapy for Obesity and Diabetes Based on a Long-Term Increase in Hepatic Fatty-Acid Oxidation §Δ
Hepatology·2010· 136 citedOpen Access
Preparation of α‐labeled aldehydes by base‐catalyzed exchange reactions
Journal of Labelled Compounds and Radiopharmaceuticals·2010· 20 citedOpen Access
Novel role of FATP1 in mitochondrial fatty acid oxidation in skeletal muscle cells
Journal of Lipid Research·2009· 121 citedOpen Access
Ten novel<i>HMGCL</i>mutations in 24 patients of different origin with 3-hydroxy-3-methyl-glutaric aciduria
Human Mutation·2009· 27 cited
OCTN1: transportador de carnitina imprescindible per a l'activitat CPT1
Estudis Romànics (Institut d'Estudis Catalans)·2009
C75 is converted to C75-CoA in the hypothalamus, where it inhibits carnitine palmitoyltransferase 1 and decreases food intake and body weight
Biochemical Pharmacology·2008· 68 citedOpen Access
Author Index
Journal of Biological Chemistry·2008Open Access
CPT1c is localized in endoplasmic reticulum of neurons and has carnitine palmitoyltransferase activity. VOLUME 283 (2008) PAGES 6878-6885
Journal of Biological Chemistry·2008Open Access
CPT1c Is Localized in Endoplasmic Reticulum of Neurons and Has Carnitine Palmitoyltransferase Activity
Journal of Biological Chemistry·2008· 196 citedOpen Access
Definition by Functional and Structural Analysis of Two Malonyl-CoA Sites in Carnitine Palmitoyltransferase 1A
Journal of Biological Chemistry·2007· 61 citedOpen Access
CPT I overexpression protects L6E9 muscle cells from fatty acid-induced insulin resistance
American Journal of Physiology-Endocrinology and Metabolism·2006· 89 cited
Mutagenesis of Specific Amino Acids Converts Carnitine Acetyltransferase into Carnitine Palmitoyltransferase
Biochemistry·2006· 12 cited
Novel Effect of C75 on Carnitine Palmitoyltransferase I Activity and Palmitate Oxidation
Biochemistry·2006· 58 cited
Alteration of the <i>M</i>alonyl-<i>CoA</i>/Carnitine Palmitoyltransferase <i>I</i> Interaction in the β-Cell Impairs Glucose-Induced Insulin Secretion
Diabetes·2005· 80 citedOpen Access
Redesign of Carnitine Acetyltransferase Specificity by Protein Engineering
Journal of Biological Chemistry·2004· 32 citedOpen Access
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Frequent Co-authors

Fausto G. Hegardt(46), Dolors Serra(45), Paulino Gómez‐Puertas(11), Laura Herrero(10), Montserrat Morillas(8), Eduardo López‐Viñas(7), Gladys Arias Arroyo(6), Josep Clotet(5), Núria Casals(5), David Sebastián(5), Blanca Rubı́(5), Paula Mera(5), Xavier Ariza(5), Jordi García(5), C. Caudevilla(4), Assia Bentebibel(4), Joaquı́n Ariño(4), Kamil Makowski(4), Angel Miliar(3), Alfons Valera(3)