Yuki Iwaki

Janssen (Belgium) — Belgium

Medicine · Health Sciences

10h-index496citations27works0.02yr avg
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Research Topics

Multiple Myeloma Research and Treatments(4), Carbohydrate Chemistry and Synthesis(4), Synthetic Organic Chemistry Methods(4), Microbial Natural Products and Biosynthesis(3), Prostate Cancer Treatment and Research(3)

Publications27 total

Simultaneous Target-Mediated Drug Disposition-Pharmacodynamic (TMDD-PD) Modeling of Finasteride and Dutasteride: Impact of Target Binding and Turnover on Non-linear Pharmacokinetics
The AAPS Journal·2025
Mechanistic modeling projections of antibody persistence after homologous booster regimens of COVID‐19 vaccine Ad26.COV2.S in humans
CPT Pharmacometrics & Systems Pharmacology·2023· 5 citedOpen Access
Population Pharmacokinetics and Exposure–Response with Teclistamab in Patients With Relapsed/Refractory Multiple Myeloma: Results From MajesTEC-1
Targeted Oncology·2023· 35 citedOpen Access
Teclistamab Population Pharmacokinetics and Exposure-Response Relationship Support 1.5 Mg/Kg Dose Regimen in Relapsed/Refractory Multiple Myeloma
Blood·2022· 5 cited
Pharmacokinetic/Pharmacodynamic Analysis of Guselkumab for Treatment of Palmoplantar Pustulosis: Clinical Implications of Guselkumab Dose, Disease Severity, and Smoking in Japanese Patients
The Journal of Clinical Pharmacology·2021· 1 cited
Correction to: Skin rash following Administration of Apalutamide in Japanese patients with Advanced Prostate Cancer: an integrated analysis of the phase 3 SPARTAN and TITAN studies and a phase 1 open-label study
BMC Urology·2020· 5 citedOpen Access
Skin rash following Administration of Apalutamide in Japanese patients with Advanced Prostate Cancer: an integrated analysis of the phase 3 SPARTAN and TITAN studies and a phase 1 open-label study
BMC Urology·2020· 62 citedOpen Access
Structure-Guided Design of Substituted Biphenyl Butanoic Acid Derivatives as Neprilysin Inhibitors
ACS Medicinal Chemistry Letters·2020· 7 citedOpen Access
Comparative and quantitative assessment on statin efficacy and safety: insights into inter-statin and inter-individual variability via dose- and exposure-response relationships
Expert Opinion on Drug Metabolism & Toxicology·2019· 13 cited
An open-label, phase 1 study of androgen receptor antagonist, apalutamide in Japanese patients with metastatic castration-resistant prostate cancer
International Journal of Clinical Oncology·2019· 16 citedOpen Access
Comparative and quantitative assessment on statin efficacy and safety: insights into inter-statin and inter-individual variability via dose- and exposure-response relationships
Figshare·2019Open Access
Pharmacokinetics and Safety of Mavatrep (JNJ‐39439335), a TRPV1 Antagonist in Healthy Japanese and Caucasian Men: A Double‐Blind, Randomized, Placebo‐Controlled, Sequential‐Group Phase 1 Study
Clinical Pharmacology in Drug Development·2017· 7 cited
Discovery of a Novel Piperidine-Based Inhibitor of Cholesteryl Ester Transfer Protein (CETP) That Retains Activity in Hypertriglyceridemic Plasma
Journal of Medicinal Chemistry·2017· 8 citedOpen Access
Optimization of Allosteric With-No-Lysine (WNK) Kinase Inhibitors and Efficacy in Rodent Hypertension Models
Journal of Medicinal Chemistry·2017· 37 citedOpen Access
CCDC 1574096: Experimental Crystal Structure Determination
The Cambridge Structural Database·2017Open Access
CCDC 1574095: Experimental Crystal Structure Determination
The Cambridge Structural Database·2017Open Access
Small-molecule WNK inhibition regulates cardiovascular and renal function
Nature Chemical Biology·2016· 162 citedOpen Access
Synthesis of Paclitaxel. 1. Synthesis of the ABC Ring of Paclitaxel by SmI<sub>2</sub>-Mediated Cyclization
Organic Letters·2015· 53 cited
ChemInform Abstract: First Synthesis of (+)‐Myxothiazol A.
ChemInform·2009
Total synthesis of (+)-myxothiazols A and Z
Tetrahedron Asymmetry·2009· 11 cited
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Frequent Co-authors

Hiroyuki Akita(7), Dean F. Rigel(6), Ken Yamada(5), Hidetomo Imase(5), Muneto Mogi(5), Kayo Yasoshima(5), Toshio Kawanami(5), Daniel LaSala(4), Guiqing Liang(4), Hiroji Uemura(3), Keiichiro Imanaka(3), Wooin Lee(3), Yuichi Sugiyama(3), Masahiro Kaneko(3), Margaret E. Brousseau(3), Wataru Honma(3), Akiko Iimura(3), Hironobu Mitani(3), K. Nonomura(3), Osamu Ohmori(3)