Ken Yamada

Novartis (Japan) — Japan

Chemistry · Physical Sciences

7h-index638citations20works0.02yr avg
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Research Topics

Catalytic C–H Functionalization Methods(4), Catalytic Cross-Coupling Reactions(4), Ion Transport and Channel Regulation(3), Synthesis and Catalytic Reactions(3), Magnetism in coordination complexes(2)

Publications20 total

Discovery of a Novel Piperidine-Based Inhibitor of Cholesteryl Ester Transfer Protein (CETP) That Retains Activity in Hypertriglyceridemic Plasma
Journal of Medicinal Chemistry·2017· 8 citedOpen Access
Optimization of Allosteric With-No-Lysine (WNK) Kinase Inhibitors and Efficacy in Rodent Hypertension Models
Journal of Medicinal Chemistry·2017· 37 citedOpen Access
Correlation Between Nasal Epithelial Injury and In Vitro Cytotoxicity Using a Series of Small Molecule Protein Tyrosine Phosphatase 1B Inhibitors Investigated for Reversal of Leptin Resistance in Obesity
International Journal of Toxicology·2017· 1 citedOpen Access
CCDC 1574096: Experimental Crystal Structure Determination
The Cambridge Structural Database·2017Open Access
CCDC 1574095: Experimental Crystal Structure Determination
The Cambridge Structural Database·2017Open Access
Discovery and Characterization of Allosteric WNK Kinase Inhibitors
ACS Chemical Biology·2016· 44 citedOpen Access
Small-molecule WNK inhibition regulates cardiovascular and renal function
Nature Chemical Biology·2016· 162 citedOpen Access
経口投与可能なATP競合的With‐No‐Lysine(WNK)キナーゼ阻害剤
メディシナルケミストリーシンポジウム講演要旨集·2016
Orally Available ATP-competitive Inhibitors of With-No-Lysine (WNK) Kinase
メディシナルケミストリーシンポジウム講演要旨集·2016
ホスホラミダイト誘導体のO‐Nホスホリル移動を用いた5′‐末端キャップオリゴヌクレオチドの合成
Organic Letters·2012· 3 cited
ChemInform Abstract: A Mild Inter‐ and Intramolecular Amination of Aryl Halides with a Combination of CuI and CsOAc.
ChemInform·2009
A mild inter- and intramolecular amination of aryl halides with a combination of CuI and CsOAc
Tetrahedron·2008· 100 cited
Total Synthesis of the Duocarmycins.
ChemInform·2003Open Access
Total Synthesis of the Duocarmycins
Journal of the American Chemical Society·2003· 133 cited
ChemInform Abstract: A Mild Copper‐Mediated Intramolecular Amination of Aryl Halides.
ChemInform·2002· 1 cited
A Mild Copper-mediated Intramolecular Amination of Aryl Halides
Synlett·2002· 146 cited
ChemInform Abstract: Synthesis of Quadruply Carbon‐13 Labeled Tetramethyltetrathiafulvalene.
ChemInform·2000
Synthesis of Quadruply Carbon-13 Labeled Tetramethyltetrathiaful Valene
Synthetic Communications·2000· 3 cited
ChemInform Abstract: Photo‐Induced Hydroxylation of Copper Complexes of 2‐Hydroxyazobenzenes.
ChemInform·1989
ChemInform Abstract: GROUND STATE SPECTROSCOPIC CONSTANTS OF ISOTHIOCYANIC ACID (NITROGEN‐15), ISOTHIOCYANIC ACID (CARBON‐13), AND ISOTHIOCYANIC ACID (SULFUR‐34), AND THE MOLECULAR STRUCTURE OF ISOTHIOCYANIC ACID
Chemischer Informationsdienst·1980

Frequent Co-authors

Kayo Yasoshima(9), Hidetomo Imase(7), Hidetoshi Tokuyama(6), Dean F. Rigel(5), Yuki Iwaki(5), Mitsunori Kato(5), Daniel LaSala(5), Muneto Mogi(5), Xiaoling Xie(5), Toshio Kawanami(5), Hyi-Man Park(4), Monish Jain(4), Tetsuji Kubo(4), Tohru Fukuyama(4), Qiying Hu(3), Neeraja Idamakanti(3), Darcy Kohls(3), Ruowei Mo(3), Bahaâ Salem(3), Yukiko Yagi(3)