Hidetoshi Tokuyama

Tohoku University — Japan

Chemistry · Physical Sciences

52h-index9.0kcitations328works0.92yr avg
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Research Topics

Chemical synthesis and alkaloids(74), Alkaloids: synthesis and pharmacology(68), Synthetic Organic Chemistry Methods(65), Catalytic C–H Functionalization Methods(44), Asymmetric Synthesis and Catalysis(43)

Publications327 total

Divergent Total Synthesis of Denudatine Alkaloids Cochlearenine, Macrocentrine, Dictizine, 15‐Veratroyl‐17‐Acetyl‐19‐Oxodictizine, and the Proposed Structure of Acochlearine
Angewandte Chemie·2025Open Access
Divergent Total Synthesis of Denudatine Alkaloids Cochlearenine, Macrocentrine, Dictizine, 15‐Veratroyl‐17‐Acetyl‐19‐Oxodictizine, and the Proposed Structure of Acochlearine
Angewandte Chemie International Edition·2025· 1 citedOpen Access
Aerobic Oxidative Dethioacetalization Catalyzed by an Iron Phthalocyanine Complex
Advanced Synthesis & Catalysis·2025Open Access
Concise Total Synthesis of (±)-Makaluvamine F and Its Derivatives
Chemical and Pharmaceutical Bulletin·2025Open Access
Synthesis of 2-Phosphorus-Substituted Indoles via Ring Expansion of Benzocyclobutenone Oxime Sulfonates
Organic Letters·2025· 1 citedOpen Access
Semisynthetic Studies Establish a Role for Conjugate Halide Exchange in the Formation of Chlorinated Pyrroloiminoquinones and Related Alkaloids
Journal of Natural Products·2024· 3 cited
The Asymmetric Total Synthesis of Discorhabdin B, H, K, and Aleutianamine
2024· 1 citedOpen Access
Antibody-mimetic drug conjugate with efficient internalization activity using anti-HER2 VHH and duocarmycin
Protein Expression and Purification·2023· 5 citedOpen Access
Unified Divergent Total Synthesis of Discorhabdin B, H, K, and Aleutianamine via the Late-Stage Oxidative <i>N,S</i>-Acetal Formation
Journal of the American Chemical Society·2023· 18 cited
Concise Total Synthesis of (+)-Pleiocarpamine and Convergent Total Syntheses of (+)-Voacalgine A and (+)-Bipleiophylline via an Aerobic Oxidative Coupling
Journal of the American Chemical Society·2023· 14 cited
Synthetic Studies on Cimiciduphytine
Bulletin of the Chemical Society of Japan·2023· 1 cited
CCDC 2174341: Experimental Crystal Structure Determination
The Cambridge Structural Database·2023Open Access
Iron‐Catalyzed Biomimetic Dimerization of Tryptophan‐Containing Peptides
Angewandte Chemie International Edition·2023· 18 citedOpen Access
Iron‐Catalyzed Biomimetic Dimerization of Tryptophan‐Containing Peptides
Angewandte Chemie·2023· 1 cited
Efficient and Scalable Asymmetric Total Synthesis of (−)-Emetine with Pharmaceutical Grade Quality; First Multigram Scale Synthesis
Organic Process Research & Development·2023· 10 cited
Catalytic enantioselective 5-endo-bromocycloetherification of unactivated cyclic alkenes
Tetrahedron Letters·2022· 3 cited
Catalytic Enantioselective 5-Endo-Bromocycloetherification of Unactivated Cyclic Alkenes
SSRN Electronic Journal·2022Open Access
Construction of Tetrahydroquinolines with Spirocyclic Structures at the 4-Position
Heterocycles·2022· 2 citedOpen Access
Total synthesis of (±)-vinoxine: construction of the bridged pyrido[1,2-<i>a</i>]indole skeleton <i>via</i> Tf<sub>2</sub>O-mediated Bischler–Napieralski reaction and stereoselective radical cyclization
Organic & Biomolecular Chemistry·2022· 9 cited
Synthetic studies on discorhabdin V: Construction of the A–F hexacyclic framework
Tetrahedron Letters·2021· 13 cited
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Frequent Co-authors

Tohru Fukuyama(17), Tohru Fukuyama(12), Kentaro Okano(8), Eiichi Nakamura(7), Satoshi Yokoshima(7), Hirofumi Ueda(6), Takashi Yamashita(5), Shigeru Yamago(4), Kenji Sugimoto(4), Takeshi Kuboyama(3), Ken Yamada(3), Yosuke Kaburagi(3), Hideto Fujiwara(3), Takashi Shiraki(2), Yukio Sugiura(2), Hiroyuki Isobe(2), Tetsuji Kubo(2), Amos B. Smith(2), Naoya Shindo(2), Kiyosei Takasu(2)