Daniel O’Toole

Ollscoil na Gaillimhe – University of Galway — Ireland

Medicine · Health Sciences

27h-index2.2kcitations106works0.92yr avg
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Research Topics

Respiratory Support and Mechanisms(40), Mesenchymal stem cell research(32), Neonatal Respiratory Health Research(24), Immune Response and Inflammation(8), Tissue Engineering and Regenerative Medicine(8)

Publications106 total

Study of the in vitro therapeutic efficacy of preconditioned MSCs for the treatment of ARDS
2025
The therapeutic potential of mesenchymal stromal cell therapy and hypercapnia in ARDS
2025
An evaluation of Tie2 mRNA as a potential therapeutic for ventilator-induced lung injury
2025
Effects of ARDS microenvironment on MSCs immunomodulatory capacity
2025
The impact of the inflammatory pulmonary microenvironment on the behavior and function of mesenchymal stromal cells
Expert Review of Respiratory Medicine·2025Open Access
Can nebulised heparin reduce acute lung injury in patients with SARS‑CoV‑2 requiring advanced respiratory support in Ireland: the CHARTER‑Ireland phase Ib/IIa, randomised, parallel-group, open-label study
Intensive Care Medicine Experimental·2025· 4 citedOpen Access
Editorial: Novel targets and state of the art therapies in ARDS and sepsis
Frontiers in Medicine·2024Open Access
Development of a nanometre scale X-ray speckle-based CT technique through the 3-D histological assessment of an acute respiratory distress syndrome model
Scientific Reports·2024Open Access
The Effects of the Pneumonia Lung Microenvironment on MSC Function
Cells·2024· 2 citedOpen Access
Cytokine preconditioning enhances the therapeutic potential of MSCs in ARDS
2024· 1 cited
A novel aerosolised mRNA-based vaccine delivery platform
2024
The inflammatory microenvironment in ARDS patients affects the metabolism of MSCs
2024
Post-operative Analgesia Following Caudal Epidural in Robotic Prostatectomy
European Urology Open Science·2024Open Access
A roadmap to precision treatments for familial pulmonary fibrosis
EBioMedicine·2024· 6 citedOpen Access
MSCs are protective against ‘second hit’ injury during pulmonary sepsis in mechanically ventilated rodents.
2023
Aerosol Delivery of a Novel Recombinant Modified Superoxide Dismutase Protein Reduces Oxidant Injury and Attenuates <i>Escherichia coli</i> Induced Lung Injury in Rats
Journal of Aerosol Medicine and Pulmonary Drug Delivery·2023
Delayed MSC therapy enhances resolution of organized pneumonia induced by antibiotic resistant Klebsiella pneumoniae infection
Frontiers in Medicine·2023· 28 citedOpen Access
Nebulised mesenchymal stem cell derived extracellular vesicles ameliorate E. coli induced pneumonia in a rodent model
Stem Cell Research & Therapy·2023· 20 citedOpen Access
Nebulized mesenchymal stem cell derived conditioned medium ameliorates Escherichia coli induced pneumonia in a rat model
Frontiers in Medicine·2023· 7 citedOpen Access
Multiple Dosing and Preactivation of Mesenchymal Stromal Cells Enhance Efficacy in Established Pneumonia Induced by Antimicrobial-Resistant Klebsiella pneumoniae in Rodents
International Journal of Molecular Sciences·2023· 7 citedOpen Access
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Frequent Co-authors

John G. Laffey(38), Claire Masterson(24), Sean McCarthy(12), James Devaney(11), Timothy O’Brien(10), H. Esteban(10), Gerard F. Curley(9), Shahd Horie(9), Brendan D. Higgins(7), Declan Byrnes(7), Frank Barry(6), Jack Brady(6), Mairéad Hayes(5), Bilal Ansari(5), Maya Contreras(5), Michael Scully(5), Ronan MacLoughlin(5), Emma J. Murphy(4), Juan Fandiño(4), Ian Major(3)