Declan Byrnes

Ollscoil na Gaillimhe – University of Galway — Ireland

Medicine · Health Sciences

7h-index164citations19works0.02yr avg
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Research Topics

Mesenchymal stem cell research(14), Respiratory Support and Mechanisms(6), Neonatal Respiratory Health Research(5), Extracellular vesicles in disease(3), MicroRNA in disease regulation(1)

Publications19 total

MSCs are protective against ‘second hit’ injury during pulmonary sepsis in mechanically ventilated rodents.
2023
Delayed MSC therapy enhances resolution of organized pneumonia induced by antibiotic resistant Klebsiella pneumoniae infection
Frontiers in Medicine·2023· 28 citedOpen Access
Nebulised mesenchymal stem cell derived extracellular vesicles ameliorate E. coli induced pneumonia in a rodent model
Stem Cell Research & Therapy·2023· 20 citedOpen Access
Multiple Dosing and Preactivation of Mesenchymal Stromal Cells Enhance Efficacy in Established Pneumonia Induced by Antimicrobial-Resistant Klebsiella pneumoniae in Rodents
International Journal of Molecular Sciences·2023· 7 citedOpen Access
Aerosolized Pulmonary Delivery of mRNA Constructs Attenuates Severity of <i>Escherichia coli</i> Pneumonia in the Rat
Nucleic Acid Therapeutics·2023· 8 citedOpen Access
Differential Effects of Cytokine Versus Hypoxic Preconditioning of Human Mesenchymal Stromal Cells in Pulmonary Sepsis Induced by Antimicrobial-Resistant Klebsiella pneumoniae
Pharmaceuticals·2023· 6 citedOpen Access
Clinically relevant administration of naive and activated mesenchymal stromal cells for the treatment of bacterial induced pulmonary sepsis
10.01 - Respiratory infections and bronchiectasis·2022
Licensed Umbilical Cord Mesenchymal Stromal Cells Enhanced the Restoration of Local and Systemic Immune Homeostasis in a Transitionary Phase Model of Pneumonia Induced Sepsis
2022
Nebulized Bone Marrow Derived Extracellular Vesicles Ameliorate Bacterial Induced Pneumonia In Vivo
2022
Combating Hyperinflammation and Ensuing Damage in Acute Antibiotic Resistant Klebsiella spp <i>.</i> Pneumonia Using Primed Human Bone Marrow Mesenchymal Stromal Cells
2022
Therapeutic potential of mesenchymal stem cells in the restoration of local immune homeostasis for transitionary phase pneumonia-induced sepsis
2022
Enhancement strategies for mesenchymal stem cells and related therapies
Stem Cell Research & Therapy·2022· 48 citedOpen Access
Hypercapnia in the critically ill: insights from the bench to the bedside
Interface Focus·2021· 19 citedOpen Access
Physiological and Immunological Effects of Naïve and Pre-Activated Mesenchymal Stromal Cells in Klebsiella Pneumoniae-Induced Sepsis in Rats
2020
Therapeutic potential of mesenchymal stem cells to attenuate immune cell tolerance in a late stage model of sepsis
2020
Mesenchymal Stromal Cells Modulate the Systemic and Pulmonary Immune Cell Profile in Klebsiella Pneumoniae Induced Sepsis
2020
Mesenchymal Stem/Stromal Cells Therapy for Sepsis and Acute Respiratory Distress Syndrome
Seminars in Respiratory and Critical Care Medicine·2020· 27 cited
Investigation of nanostar-labeled mesenchymal stem cells for in vivo cell tracking in osteoarthritis using optoacoustic imaging
Osteoarthritis and Cartilage·2020· 1 cited
Mesenchymal Stromal Cell Effects on the Innate and Adaptive Immune Response to Sepsis
2019

Frequent Co-authors

Claire Masterson(17), John G. Laffey(17), Daniel O’Toole(14), H. Esteban(14), Sean McCarthy(13), Jack Brady(8), Shahd Horie(6), Juan Fandiño(5), Ronan MacLoughlin(3), Senthilkumar Alagesan(2), Ignacio Sallent(2), D. O'Toole(2), Antonio Artigas(1), Emma Horan(1), Stephen J. Elliman(1), Gabriele Vella(1), Adriele Prina‐Mello(1), Johnatas D. Silva(1), Anna Krasnodembskaya(1), Christopher B. Rohde(1)