Che-Chia Hsu

Duke University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

9h-index1.7kcitations17works12.02yr avg
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Research Topics

Cancer, Hypoxia, and Metabolism(5), Metabolism, Diabetes, and Cancer(5), Ubiquitin and proteasome pathways(4), Epigenetics and DNA Methylation(3), Pancreatic function and diabetes(3)

Publications17 total

Glucose metabolism and its direct action in cancer and immune regulation: opportunities and challenges for metabolic targeting
Journal of Biomedical Science·2025· 7 citedOpen Access
ALDH4A1 functions as an active component of the MPC complex maintaining mitochondrial pyruvate import for TCA cycle entry and tumour suppression
Nature Cell Biology·2025· 6 cited
CD36-mediated endocytosis of proteolysis-targeting chimeras
Cell·2025· 30 cited
IMPA1-derived inositol maintains stemness in castration-resistant prostate cancer via IMPDH2 activation
The Journal of Experimental Medicine·2024· 5 citedOpen Access
NSUN2 is a glucose sensor suppressing cGAS/STING to maintain tumorigenesis and immunotherapy resistance
Cell Metabolism·2023· 179 citedOpen Access
Identification of myo-inositol-binding proteins by using the biotin pull-down strategy in cultured cells
STAR Protocols·2022· 6 citedOpen Access
UHRF1: a novel metabolic guardian restricting AMPK activity
Cell Research·2021· 1 citedOpen Access
NOX2-Deficient Neutrophils Facilitate Joint Inflammation Through Higher Pro-Inflammatory and Weakened Immune Checkpoint Activities
Frontiers in Immunology·2021· 18 citedOpen Access
Inositol serves as a natural inhibitor of mitochondrial fission by directly targeting AMPK
Molecular Cell·2021· 82 citedOpen Access
AMPK signaling and its targeting in cancer progression and treatment
Seminars in Cancer Biology·2021· 235 citedOpen Access
Phosphorylation of PDHA by AMPK Drives TCA Cycle to Promote Cancer Metastasis
Molecular Cell·2020· 260 citedOpen Access
Increased activation of HDAC1/2/6 and Sp1 underlies therapeutic resistance and tumor growth in glioblastoma
Neuro-Oncology·2020· 106 citedOpen Access
Increased activation of HDAC1, 2, and 6, and Sp1 underlies therapeutic resistance and tumor growth in glioblastoma
The FASEB Journal·2020· 1 cited
The Skp2 Pathway: A Critical Target for Cancer Therapy
Seminars in Cancer Biology·2020· 195 citedOpen Access
Lactate Is a Natural Suppressor of RLR Signaling by Targeting MAVS
Cell·2019· 559 citedOpen Access
Inhibition of the HDAC6/Sp1 pathway by azaindolylsulfonamide reduces cancer stemness and restores treatment susceptibility in glioblastoma
Proceedings for Annual Meeting of The Japanese Pharmacological Society·2018Open Access
Additional file 1: of Suberoylanilide hydroxamic acid represses glioma stem-like cells
Figshare·2016Open Access

Frequent Co-authors

Hui‐Kuan Lin(11), Bo‐Syong Pan(9), Hongyu Li(7), Zhong‐Zhu Chen(5), Zhen Cai(5), Guihua Wang(4), Zhigang Xu(4), Danni Peng(4), Tingjin Chen(4), Rajesh Manne(4), Jian‐Ying Chuang(4), Guoxiang Jin(3), Xian Zhang(3), Kwang‐Yu Chang(3), Wen‐Chang Chang(3), Haiwei Gu(3), Chuan Xu(2), Chien‐Feng Li(2), Weina Zhang(2), Chi‐Yun Wang(2)