Luca Giorgetti

Friedrich Miescher Institute — Switzerland

Biochemistry, Genetics and Molecular Biology · Life Sciences

25h-index7.7kcitations74works5.32yr avg
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Research Topics

Genomics and Chromatin Dynamics(44), RNA Research and Splicing(25), Chromosomal and Genetic Variations(13), RNA and protein synthesis mechanisms(10), Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities(7)

Publications74 total

Cancer Virtual Lab: una piattaforma sicura e interoperabile basata su knowledge graph e large language model per la ricerca oncologica
Recenti Progressi in Medicina·2025
Loop extrusion creates rare, long-lived encounters underlying enhancer-promoter communication
2025· 1 citedOpen Access
From raw data to research-ready: A FHIR-based transformation pipeline in a real-world oncology setting
Computers in Biology and Medicine·2025· 1 citedOpen Access
Single-molecule chromosome tracing reveals a diversity of megabase heterochromatin domains
2025· 1 citedOpen Access
Dosage sensitivity of the loop extrusion rate confers tunability to genome folding while creating vulnerability to genetic disruption
2025· 9 citedOpen Access
Enhancer control of promoter activity and variability <i>via</i> frequency modulation of clustered transcriptional bursts
2025· 5 cited
Increasingly efficient chromatin binding of cohesin and CTCF supports chromatin architecture formation during zebrafish embryogenesis
Nature Communications·2025· 3 citedOpen Access
Genome-wide absolute quantification of chromatin looping
2025· 13 citedOpen Access
Chromatin-Based Cellular Dependency of HOXA9/MEIS1-Driven Acute Myeloid Leukemia
Blood·2024· 1 cited
Author Correction: Systematic assessment of ISWI subunits shows that NURF creates local accessibility for CTCF
Nature Genetics·2024Open Access
Systematic assessment of ISWI subunits shows that NURF creates local accessibility for CTCF
Nature Genetics·2024· 24 citedOpen Access
Increasingly efficient chromatin binding of cohesin and CTCF supports chromatin architecture formation during zebrafish embryogenesis
2023· 3 citedOpen Access
Intra- and interchromosomal contact mapping reveals the Igh locus has extensive conformational heterogeneity and interacts with B-lineage genes
Cell Reports·2023· 8 citedOpen Access
Integrative approaches to study enhancer–promoter communication
Current Opinion in Genetics & Development·2023· 9 citedOpen Access
Cohesin and CTCF control the dynamics of chromosome folding
Nature Genetics·2022· 252 citedOpen Access
Inversion of a topological domain leads to restricted changes in its gene expression and affects interdomain communication
Development·2022· 23 citedOpen Access
VisuStatR: visualizing motility and morphology statistics on images in R
Bioinformatics·2022Open Access
Nonlinear control of transcription through enhancer–promoter interactions
Nature·2022· 429 citedOpen Access
Live-cell imaging and physical modeling reveal control of chromosome folding dynamics by cohesin and CTCF
2022· 22 citedOpen Access
Inversion of a topological domain leads to restricted changes in its gene expression and affects inter-domain communication
2022· 3 citedOpen Access
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Frequent Co-authors

Édith Heard(17), Yinxiu Zhan(17), Guido Tiana(14), Elphège P. Nora(10), Nicolas Servant(7), Roberta Carbone(7), Pia Mach(6), G. Bongiorno(6), Job Dekker(5), Rafael Galupa(5), Grégory Roth(5), Julie Cramard(5), Mariya Kryzhanovska(5), Sébastien A. Smallwood(5), P. Milani(5), A. Zanardi(5), Bryan R. Lajoie(4), Edda G. Schulz(4), Tristan Piolot(4), Jessica Zuin(4)