Job Dekker

Howard Hughes Medical Institute — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

96h-index71.5kcitations384works16.02yr avg
OpenAlex↗ORCID↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Genomics and Chromatin Dynamics(233), RNA Research and Splicing(96), Chromosomal and Genetic Variations(94), RNA and protein synthesis mechanisms(61), Epigenetics and DNA Methylation(32)

Publications382 total

An integrated view of the structure and function of the human 4D nucleome
Nature·2025· 4 citedOpen Access
mRNA initiation and termination are spatially coordinated
Science·2025· 5 cited
Dynamic changes in chromosome and nuclear architecture during maturation of normal and ALS C9orf72 motor neurons
2025· 1 citedOpen Access
esBAF and INO80C fine-tune subcompartments and differentially regulate enhancer-promoter interactions
2025Open Access
Histone Acetylation Differentially Modulates CTCF-CTCF Loops and Intra-TAD Interactions
2025Open Access
Mitotic chromosomes harbor cell type– and species-specific structural features within a universal loop array conformation
Genome Research·2025· 3 citedOpen Access
Rules of engagement for condensins and cohesins guide mitotic chromosome formation
Science·2025· 41 citedOpen Access
TOP2B is required for compartment strength changes upon retinoic acid treatment in SH-SY5Y cells
Chromosome Research·2025Open Access
The chromosome folding problem and how cells solve it
Cell·2024· 83 citedOpen Access
Polymer Physics Models Reveal Structural Folding Features of Single-Molecule Gene Chromatin Conformations
International Journal of Molecular Sciences·2024· 3 citedOpen Access
An integrated view of the structure and function of the human 4D nucleome
2024· 16 citedOpen Access
Interphase chromosome conformation is specified by distinct folding programs inherited via mitotic chromosomes or through the cytoplasm
2024· 6 citedOpen Access
Polymer physics models reveal structural folding features of single-molecule gene chromatin conformations
2024· 1 citedOpen Access
Rules of engagement for condensins and cohesins guide mitotic chromosome formation
2024· 22 citedOpen Access
Mitotic chromosomes are self-entangled and disentangle through a topoisomerase-II-dependent two-stage exit from mitosis
Molecular Cell·2024· 44 citedOpen Access
Rules of engagement for cohesin and condensin complexes during mitotic chromosome formation
EMPIAR dataset·2024Open Access
Chromosome evolution screens recapitulate tissue-specific tumor aneuploidy patterns
Nature Genetics·2024· 50 citedOpen Access
mRNA initiation and termination are spatially coordinated
2024· 9 citedOpen Access
RNA-mediated symmetry breaking enables singular olfactory receptor choice
Nature·2023· 44 citedOpen Access
Mitotic chromosomes harbor cell type and species-specific structural features within a universal looping architecture
2023· 4 citedOpen Access
page 1 of 20Next →

Frequent Co-authors

Bryan R. Lajoie(24), Leonid A. Mirny(13), Ye Zhan(10), Amartya Sanyal(8), J Stamatoyannopoulos(7), Rachel Patton McCord(7), Maxim Imakaev(6), Édith Heard(6), Johan H. Gibcus(6), Geoffrey Fudenberg(5), N. M. Naumova(5), Nynke L. van Berkum(4), Peter J. Sabo(4), Luca Giorgetti(4), Rajinder Kaul(4), Gregory E. Crawford(4), Ross C. Hardison(4), Gaurav Jain(4), Richard Sandstrom(3), B Bernstein(3)