Adam C. Weiner

Gladstone Institutes — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

7h-index283citations24works6.92yr avg
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Research Topics

Cancer Genomics and Diagnostics(15), Single-cell and spatial transcriptomics(13), Immunotherapy and Immune Responses(3), Evolution and Genetic Dynamics(3), T-cell and B-cell Immunology(2)

Publications24 total

1029 Unveiling genes in dendritic cells that enhance T cell priming through functional multiplexed single cell-cell interaction analysis
Regular and Young Investigator Award Abstracts·2025Open Access
Ongoing genome doubling shapes evolvability and immunity in ovarian cancer
Nature·2025· 18 citedOpen Access
Abstract B054: Identification of spatial motifs linked to tumor genotype using graph attention networks
Clinical Cancer Research·2025
Live-cell analyses with unsegmented images to study cancer cell response to modified T cell therapy
2025Open Access
Live-cell analyses with unsegmented images to study cancer cell response to modified T cell therapy
2025
Characterizing Neuroplasticity in SYNGAP1 Mutants through Integrated Computational and Experimental Approaches
Physiology·2025
CINner: Modeling and simulation of chromosomal instability in cancer at single-cell resolution
PLoS Computational Biology·2025· 6 citedOpen Access
Luminal breast epithelial cells of BRCA1 or BRCA2 mutation carriers and noncarriers harbor common breast cancer copy number alterations
Nature Genetics·2024· 21 citedOpen Access
Inferring replication timing and proliferation dynamics from single-cell DNA sequencing data
Nature Communications·2024· 7 citedOpen Access
Ongoing genome doubling promotes evolvability and immune dysregulation in ovarian cancer
2024· 10 citedOpen Access
Luminal breast epithelial cells from wildtype and <i>BRCA</i> mutation carriers harbor copy number alterations commonly associated with breast cancer
2024Open Access
Single-cell mtDNA dynamics in tumors is driven by coregulation of nuclear and mitochondrial genomes
Nature Genetics·2024· 21 citedOpen Access
CINner: modeling and simulation of chromosomal instability in cancer at single-cell resolution
2024· 6 citedOpen Access
Abstract 869: Single-cell DNA replication dynamics in genomically unstable cancers
Cancer Research·2024
Allele-specific transcriptional effects of subclonal copy number alterations enable genotype-phenotype mapping in cancer cells
Nature Communications·2024· 15 citedOpen Access
Single-cell DNA replication dynamics in genomically unstable cancers
2023· 5 citedOpen Access
Abstract 3122: Single-cell DNA replication dynamics for genomically unstable cancer cells
Cancer Research·2023
Exploiting allele-specific transcriptional effects of subclonal copy number alterations for genotype-phenotype mapping in cancer cell populations
2023Open Access
Single-cell genomic variation induced by mutational processes in cancer
Nature·2022· 143 citedOpen Access
Abstract 2128: Single-cell replication dynamics in genomically unstable cancers
Cancer Research·2022
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Frequent Co-authors

Andrew McPherson(18), Sohrab P. Shah(15), Marc Williams(13), Ignacio Vázquez-Garćıa(10), Nicole Rusk(9), Samuel Aparício(9), Diljot Grewal(8), Ciara H. O’Flanagan(6), Sohrab Salehi(6), Hongyu Shi(6), Daniel Lai(6), Nicholas Ceglia(6), Sean Beatty(5), Eliyahu Havasov(5), Florian Uhlitz(5), Tyler Funnell(4), Allen W. Zhang(4), Jamie Lim(4), Dmitriy Zamarin(4), Britta Weigelt(4)