Hishani Kirby

UCB Pharma (United Kingdom) — United Kingdom

Medicine · Health Sciences

9h-index580citations13works0.02yr avg
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Research Topics

Monoclonal and Polyclonal Antibodies Research(7), Cell Adhesion Molecules Research(4), Biosimilars and Bioanalytical Methods(4), Bone health and osteoporosis research(2), Systemic Lupus Erythematosus Research(2)

Publications13 total

Dampening of the bone formation response following repeat dosing with sclerostin antibody in mice is associated with up-regulation of Wnt antagonists
Bone·2017· 59 citedOpen Access
Up-regulation of Wnt antagonists contributes to the attenuated response of bone formation to repeat doses of sclerostin antibody in a mouse model
Bone Abstracts·2016
Standardizing terms, definitions and concepts for describing and interpreting unwanted immunogenicity of biopharmaceuticals: recommendations of the Innovative Medicines Initiative ABIRISK consortium
Clinical & Experimental Immunology·2015· 77 citedOpen Access
ABIRISK Consortium Recommendations for Terms and Definitions for Describing and Interpreting Unwanted Immunogenicity of Biopharmaceuticals
2015
First-in-human trial of the safety, pharmacokinetics and immunogenicity of a PEGylated anti-CD40L antibody fragment (CDP7657) in healthy individuals and patients with systemic lupus erythematosus
Lupus·2015· 71 cited
A fit-for-purpose strategy for the risk-based immunogenicity testing of biotherapeutics: a European industry perspective
Journal of Immunological Methods·2015· 33 cited
The S228P Mutation Prevents in Vivo and in Vitro IgG4 Fab-arm Exchange as Demonstrated using a Combination of Novel Quantitative Immunoassays and Physiological Matrix Preparation
Journal of Biological Chemistry·2015· 83 citedOpen Access
A time-to-event model for the immunogenicity of certolizumab pegol in rheumatoid arthritis subjects
2015
Syndecans promote integrin-mediated adhesion of mesenchymal cells in two distinct pathways
Experimental Cell Research·2007· 68 cited
Molecular Basis for the Dynamic Strength of the Integrin α4β1/VCAM-1 Interaction
Biophysical Journal·2004· 116 citedOpen Access
Generation of a Minimal α5β1 Integrin-Fc Fragment
Journal of Biological Chemistry·2001· 48 citedOpen Access
Expression of a Soluble Functional Form of the Integrin<i>α</i><sub>4</sub><i>β</i><sub>1</sub>in Mammalian Cells
Cell adhesion and communications/Cell adhesion and communication/Cell adhesion & communication·2000· 20 citedOpen Access
Biochemical individuality; variation in the urinary excretion of lysine, threonine, leucine, and arginine.
PubMed·1949· 5 cited

Frequent Co-authors

Joby K. Jose(3), Daniel Kramer(3), Sebastian Spindeldreher(3), Martyn K. Robinson(3), Martin J. Humphries(2), T. Albert(2), Matthieu Allez(2), Claudio Carini(2), Paul I. Creeke(2), Julie Davidson(2), Niek de Vries(2), Deborah Finco(2), Eva Havrdová(2), Agnès Hincelin-Méry(2), Elizabeth C. Jury(2), Sébastien Lacroix‐Desmazes(2), Julie Legrand(2), Enrico Maggi(2), Bernard Maillère(2), Claudia Mauri(2)