Steve Stippec

Southwestern Medical Center — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

21h-index2.4kcitations34works2.82yr avg
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Research Topics

Ion Transport and Channel Regulation(11), Protein Kinase Regulation and GTPase Signaling(9), Melanoma and MAPK Pathways(7), Ion channel regulation and function(6), Pancreatic function and diabetes(6)

Publications34 total

Kinase interaction analysis predicts actions of the WNK-OSR1/SPAK pathway
Communications Biology·2025· 1 citedOpen Access
Activation of WNK1 signaling through Piezo1
Proceedings of the National Academy of Sciences·2025· 2 citedOpen Access
Predictive and Experimental Motif Interaction Analysis Identifies Functions of the WNK-OSR1/SPAK Pathway
2024· 7 citedOpen Access
Testis-specific serine kinase 6 (TSSK6) is abnormally expressed in colorectal cancer and promotes oncogenic behaviors
Journal of Biological Chemistry·2024· 5 citedOpen Access
Testis Specific Serine Kinase 6 (TSSK6) is abnormally expressed in colorectal cancer and promotes oncogenic behaviors
2024· 1 citedOpen Access
Mimicking Protein Kinase C Phosphorylation Inhibits Arc/Arg3.1 Palmitoylation and Its Interaction with Nucleic Acids
International Journal of Molecular Sciences·2024· 1 citedOpen Access
ERK2 Mutations Affect Interactions, Localization, and Dimerization
Biochemistry·2023· 4 cited
Role of WNK1/OSR1 in maintaining endothelial tight junction integrity
The FASEB Journal·2020
Functional divergence caused by mutations in an energetic hotspot in ERK2
Proceedings of the National Academy of Sciences·2019· 25 citedOpen Access
Rat ERK2 E320K
2019· 19 citedOpen Access
ERK2 phosphorylates the epigenetic regulator CXXC-finger protein 1 (CFP1)
2019Open Access
The function of WNK1/OSR1 in cell migration and angiogenesis
The FASEB Journal·2018
OSR1 regulates a subset of inward rectifier potassium channels via a binding motif variant
Proceedings of the National Academy of Sciences·2018· 37 citedOpen Access
Assaying Protein Kinase Activity with Radiolabeled ATP
Journal of Visualized Experiments·2017· 15 cited
Assaying Protein Kinase Activity with Radiolabeled ATP
Journal of Visualized Experiments·2017· 4 cited
WNK1 is an unexpected autophagy inhibitor
Autophagy·2017· 43 citedOpen Access
Multistep regulation of autophagy by WNK1
Proceedings of the National Academy of Sciences·2016· 50 citedOpen Access
Phosphorylation or Mutation of the ERK2 Activation Loop Alters Oligonucleotide Binding
Biochemistry·2016· 21 citedOpen Access
Regulation of OSR1 and the sodium, potassium, two chloride cotransporter by convergent signals
Proceedings of the National Academy of Sciences·2013· 34 citedOpen Access
Protein kinase WNK3 regulates the neuronal splicing factor Fox-1
Proceedings of the National Academy of Sciences·2012· 24 citedOpen Access
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Frequent Co-authors

Melanie H. Cobb(31), Svetlana Earnest(15), Bing-e Xu(6), Sachith Gallolu Kankanamalage(6), Clinton A. Taylor(6), Kathleen McGlynn(5), Byung‐Hoon Lee(5), Chonlarat Wichaidit(5), Elizabeth J. Goldsmith(4), Yu‐Chi Juang(4), Angelique W. Whitehurst(4), Aroon S. Karra(4), Ankita B. Jaykumar(4), Bing-e Xu(3), Chou-Long Huang(3), Samarpita Sengupta(3), A-Young Lee(3), Andrés Lorente-Rodríguez(3), Hamid Mirzaei(3), Kevin W. Cormier(3)