Rolf Backofen

University of Freiburg — Germany

Biochemistry, Genetics and Molecular Biology · Life Sciences

69h-index23.9kcitations475works4.02yr avg
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Research Topics

RNA and protein synthesis mechanisms(218), RNA modifications and cancer(138), RNA Research and Splicing(114), Genomics and Phylogenetic Studies(91), CRISPR and Genetic Engineering(49)

Publications475 total

An evolutionary approach to predict the orientation of CRISPR arrays
PLoS Computational Biology·2025· 2 citedOpen Access
An updated evolutionary classification of CRISPR–Cas systems including rare variants
Nature Microbiology·2025· 17 citedOpen Access
DeepEGFR a graph neural network for bioactivity classification of EGFR inhibitors
Scientific Reports·2025Open Access
RAPDOR: Using Jensen-Shannon Distance for the computational analysis of complex proteomics datasets
Nature Communications·2025Open Access
Galaxy single-cell & spatial omics community update: Navigating new frontiers in 2025
Cell Genomics·2025Open Access
AVDB: The Arab Variation and Disease Burden Database
2025Open Access
Small Data Explainer -- The impact of small data methods in everyday life
arXiv (Cornell University)·2025Open Access
The lincRNA <i>Pantr1</i> is a FOXG1 target gene conferring site-specific chromatin binding of FOXG1
Nucleic Acids Research·2025· 1 citedOpen Access
A searchable atlas of pathogen-sensitive lncRNA networks in human macrophages
Nature Communications·2025· 6 citedOpen Access
An evolutionary approach to predict the orientation of CRISPR arrays
2025Open Access
Structural determinants of inverted Alu-mediated backsplicing revealed by -MaP and -JuMP
Nucleic Acids Research·2025· 1 citedOpen Access
The complexity of multiple CRISPR arrays in strains with (co-occurring) CRISPR systems
2025· 3 citedOpen Access
Evaluating discrepancies in dimensionality reduction for time-series single-cell RNA-sequencing data
Briefings in Bioinformatics·2025Open Access
Comprehensive Analysis of CRISPR Array Repeat Mutations Reveals Subtype-Specific Patterns and Links to Spacer Dynamics
2025· 3 citedOpen Access
Complementary Ribo-seq approaches map the translatome and provide a small protein census in the foodborne pathogen Campylobacter jejuni
Nature Communications·2025· 12 citedOpen Access
A transcriptional atlas of gut-innervating neurons reveals activation of interferon signaling and ferroptosis during intestinal inflammation
Neuron·2025· 13 citedOpen Access
Analysis of tracrRNAs reveals subgroup V2 of type V-K CAST systems
2025Open Access
Evaluating discrepancies in dimensionality reduction for time-series single-cell RNA-sequencing data
2025Open Access
Learning to generate feasible graphs using graph grammars
arXiv (Cornell University)·2025Open Access
Analysis of tracrRNAs reveals subgroup V2 of type V-K CAST systems
microLife·2025Open Access
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Frequent Co-authors

Björn Grüning(9), Sebastian Will(8), Andreas S. Richter(7), Patrick R. Wright(6), Thomas Manke(6), Omer S. Alkhnbashi(5), Daniel Maticzka(5), Joachim Wolff(5), Peter F. Stadler(5), Wolfgang R. Hess(5), Vivek Bhardwaj(4), Anke Busch(4), Fidel Ramírez(4), Ivo L. Hofacker(4), Ralf Gilsbach(4), Sita J. Lange(4), Michaël Uhl(4), Michael Hiller(4), Fabrizio Costa(3), Shiraz A. Shah(3)