Thomas Manke

HTW Berlin - University of Applied Sciences — Germany

Biochemistry, Genetics and Molecular Biology · Life Sciences

52h-index22.9kcitations157works27.02yr avg
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Research Topics

Genomics and Chromatin Dynamics(44), Quantum Chromodynamics and Particle Interactions(37), Particle physics theoretical and experimental studies(30), Epigenetics and DNA Methylation(27), High-Energy Particle Collisions Research(25)

Publications154 total

Enhancing single-cell ATAC sequencing with formaldehyde fixation, cryopreservation, and multiplexing for flexible analysis
BMC Research Notes·2025· 1 citedOpen Access
Enhancing single-cell ATAC sequencing with formaldehyde fixation, cryopreservation, and multiplexing for flexible analysis
2024· 1 citedOpen Access
Functional multi-organelle units control inflammatory lipid metabolism of macrophages
Nature Cell Biology·2024· 45 citedOpen Access
RNA damage compartmentalization by DHX9 stress granules
Cell·2024· 61 citedOpen Access
MSL2 ensures biallelic gene expression in mammals
Nature·2023· 17 citedOpen Access
Multimodal epigenetic changes and altered NEUROD1 chromatin binding in the mouse hippocampus underlie FOXG1 syndrome
Proceedings of the National Academy of Sciences·2023· 16 citedOpen Access
3128 – HYALURONIC ACID- GPRC5C SIGNALLING PROMOTES DORMANCY IN HEMATOPOIETIC STEM CELLS
Experimental Hematology·2023Open Access
EBF1 primes B-lymphoid enhancers and limits the myeloid bias in murine multipotent progenitors
The Journal of Experimental Medicine·2022· 19 citedOpen Access
Hyaluronic acid–GPRC5C signalling promotes dormancy in haematopoietic stem cells
Nature Cell Biology·2022· 63 citedOpen Access
3033 – DECIPHERING THE ROLE OF MDA5 IN HSC AGING
Experimental Hematology·2022
2024 – GPRC5C IS CRITICAL FOR HEALTHY HEMATOPOIESIS AND ACUTE MYELOID LEUKEMIA
Experimental Hematology·2022
EBF1 primes B-lymphoid enhancers and limits the myeloid bias in multipotent haematopoietic progenitors
2021Open Access
EBF1 primes B-lymphoid enhancers and limits the myeloid bias in murine multipotent progenitors
2021Open Access
EBF1 primes B-lymphoid enhancers and limits the myeloid bias in murine multipotent progenitors
Zenodo (CERN European Organization for Nuclear Research)·2021Open Access
Integrative multi-omics analyses reveal multi-modal FOXG1 functions acting on epigenetic processes and in concert with NEUROD1 to regulate synaptogenesis in the mouse hippocampus
2021Open Access
DOT1L-mediated murine neuronal differentiation associates with H3K79me2 accumulation and preserves SOX2-enhancer accessibility
Nature Communications·2020· 45 citedOpen Access
pyGenomeTracks: reproducible plots for multivariate genomic datasets 
Bioinformatics·2020· 542 citedOpen Access
AutoRELACS: automated generation and analysis of ultra-parallel ChIP-seq
Scientific Reports·2020· 5 citedOpen Access
AutoRELACS: Automated Generation And Analysis Of Ultra-parallel ChIP-seq
2020Open Access
Galaxy HiCExplorer 3: a web server for reproducible Hi-C, capture Hi-C and single-cell Hi-C data analysis, quality control and visualization
Nucleic Acids Research·2020· 452 citedOpen Access
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Frequent Co-authors

Fidel Ramírez(13), Vivek Bhardwaj(9), Asifa Akhtar(9), Björn Grüning(8), S. Hashimoto(8), K. Kanaya(8), T. Kaneko(8), T. Yoshié(8), Laura Arrigoni(7), Rolf Backofen(7), Martin Vingron(7), Shinji Ejiri(7), M. Okawa(7), A. Ali Khan(6), R. Burkhalter(6), M. Fukugita(6), N. Ishizuka(6), Y. Iwasaki(6), Hugh Shanahan(6), A. Ukawa(6)