William C. Sha

Immunology and Microbiology · Life Sciences

33h-index9.6kcitations43works0.02yr avg
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Research Topics

T-cell and B-cell Immunology(23), Immunotherapy and Immune Responses(18), Immune Cell Function and Interaction(15), Immune Response and Inflammation(14), NF-κB Signaling Pathways(13)

Publications43 total

Differentiation and Memory Formation Antigen-Dependent Murine B Cell Transcriptional Profiling of
2014
Host metabolism regulates growth and differentiation of Toxoplasma gondii
International Journal for Parasitology·2012· 40 cited
B7h-expressing dendritic cells and plasma B cells mediate distinct outcomes of ICOS costimulation in T cell-dependent antibody responses
BMC Immunology·2012· 13 citedOpen Access
TLR9 induces germinal center light zone expansion and augments B cell fate decisions (61.8)
The Journal of Immunology·2011
Mapping of the ICOS binding surface of murine B7h using an unbiased, cellular library of B7h mutants created by cyclical packaging rescue
Journal of Immunological Methods·2008· 2 cited
Transcriptional Profiling of Antigen-Dependent Murine B Cell Differentiation and Memory Formation
The Journal of Immunology·2007· 166 citedOpen Access
ICOS-Induced B7h Shedding on B Cells Is Inhibited by TLR7/8 and TLR9
The Journal of Immunology·2006· 44 cited
CD28-B7 bidirectional signaling: a two-way street to activation
Nature Immunology·2004· 28 cited
Redundant Role of Tissue-Selective TAF <sub>II</sub> 105 in B Lymphocytes
Molecular and Cellular Biology·2002· 15 citedOpen Access
Constitutive Expression of the B7h Ligand for Inducible Costimulator on Naive B Cells Is Extinguished after Activation by Distinct B Cell Receptor and Interleukin 4 Receptor–mediated Pathways and Can Be Rescued by CD40 Signaling
The Journal of Experimental Medicine·2002· 83 citedOpen Access
Identification of gene function by cyclical packaging rescue of retroviral cDNA libraries
Proceedings of the National Academy of Sciences·2002· 15 citedOpen Access
The right place at the right time: novel B7 family members regulate effector T cell responses
Current Opinion in Immunology·2002· 113 cited
The combined absence of NF-κB1 and c-Rel reveals that overlapping roles for these transcription factors in the B cell lineage are restricted to the activation and function of mature cells
Proceedings of the National Academy of Sciences·2002· 110 citedOpen Access
Requirement of Tissue-Selective TBP-Associated Factor TAF <sub>II</sub> 105 in Ovarian Development
Science·2001· 192 cited
Enhancement of CD8+ T Cell Responses by ICOS/B7h Costimulation
The Journal of Immunology·2001· 152 cited
B7h, a Novel Costimulatory Homolog of B7.1 and B7.2, Is Induced by TNFα
Immunity·1999· 445 citedOpen Access
The Ets transcription factor ERM is Th1-specific and induced by IL-12 through a Stat4-dependent pathway
Proceedings of the National Academy of Sciences·1999· 108 citedOpen Access
Inhibition of Th1 Development Mediated by GATA-3 through an IL-4-Independent Mechanism
Immunity·1998· 778 citedOpen Access
GATA-3-dependent enhancer activity in IL-4 gene regulation.
PubMed·1998· 200 cited
Cutting Edge: GATA-3-Dependent Enhancer Activity in IL-4 Gene Regulation
The Journal of Immunology·1998· 166 cited
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Frequent Co-authors

Dennis Y. Loh(11), David Baltimore(10), Rodney D. Newberry(7), John H. Russell(5), Wenjun Ouyang(4), Deepta Bhattacharya(4), Kenneth M. Murphy(4), Christopher A. Nelson(4), Linda Liang(4), Sonia Bakkour(4), Sheila Ranganath(3), David M. Kranz(3), C A Nelson(3), Eric C. Logue(3), Amer A. Beg(2), Elaine Tuomanen(2), Theresa L. Murphy(2), Jeffrey J. Wallin(2), Clifford M. Snapper(2), Hsiou‐Chi Liou(2)