Taofei Yin

Center for Genomic Science — Italy

Biochemistry, Genetics and Molecular Biology · Life Sciences

23h-index1.8kcitations38works0.02yr avg
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Research Topics

Cellular Mechanics and Interactions(10), Protein Kinase Regulation and GTPase Signaling(9), Wnt/β-catenin signaling in development and cancer(7), Cell Adhesion Molecules Research(6), Hippo pathway signaling and YAP/TAZ(6)

Publications38 total

Leveraging oncology clinical case report data through the Cancer Knowledgebase (CKB)
Personalized Medicine·2025
Breaching the Curation Bottleneck with Human-Machine Reading Symbiosis
SSRN Electronic Journal·2024Open Access
Breaching the curation bottleneck with human-machine reading symbiosis
2021· 1 citedOpen Access
N-Cadherin Levels in Endothelial Cells Are Regulated by Monolayer Maturity and p120 Availability
UNC Libraries·2020Open Access
Imaging Myosin-X at the Single-Molecule Level Reveals a Novel Form of Motility in Filopodia
UNC Libraries·2020Open Access
Utility of the JAX Clinical Knowledgebase in capture and assessment of complex genomic cancer data
npj Precision Oncology·2018· 47 citedOpen Access
The balance between Gα <sub>i</sub> -Cdc42/Rac and Gα <sub>1</sub> <sub>2</sub> / <sub>1</sub> <sub>3</sub> -RhoA pathways determines endothelial barrier regulation by sphingosine-1-phosphate
Molecular Biology of the Cell·2017· 68 citedOpen Access
Abstract 2600: Analysis of drug resistance mechanisms and strategies for overcoming resistance in cancer therapy using a curated clinical knowledgebase
Cancer Research·2017· 2 cited
Abstract 2598: Paradigm to ensure curation transparency and consistency of a cancer genomic database - the JAX Clinical Knowledgebase (CKB)
Cancer Research·2017
Abstract 2583: A model for capturing and integrating complex molecular alterations related to clinically relevant efficacy evidence
Cancer Research·2017
Abstract 541: A comprehensive analysis delineating the immunotherapeutic terrain of cancer-related clinical trials
Cancer Research·2017
Optogenetic activation of Plexin-B1 reveals contact repulsion between osteoclasts and osteoblasts
Nature Communications·2017· 46 citedOpen Access
The JAX Clinical Knowledgebase: A Valuable Resource for Identifying Evidence Related to Complex Molecular Signatures in Different Types of Cancer
Cancer Genetics·2017· 4 cited
Phosphorylated cortactin recruits Vav2 guanine nucleotide exchange factor to activate Rac3 and promote invadopodial function in invasive breast cancer cells
Molecular Biology of the Cell·2017· 43 citedOpen Access
Kinetics of recruitment and allosteric activation of ARHGEF25 isoforms by the heterotrimeric G-protein Gαq
Scientific Reports·2016· 27 citedOpen Access
Palmitoylation of the oncogenic RhoGEF TGAT is dispensable for membrane localization and consequent activation of RhoA
2016Open Access
Spatiotemporal analysis of RhoA/B/C activation in primary human endothelial cells
Scientific Reports·2016· 68 citedOpen Access
F-actin-rich contractile endothelial pores prevent vascular leakage during leukocyte diapedesis through local RhoA signalling
Nature Communications·2016· 139 citedOpen Access
Rapid Remodeling of Invadosomes by Gi-coupled Receptors
Journal of Biological Chemistry·2016· 42 citedOpen Access
Plasma membrane restricted RhoGEF activity is sufficient for RhoA-mediated actin polymerization
Scientific Reports·2015· 112 citedOpen Access
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Frequent Co-authors

Yi Wu(18), Joachim Goedhart(9), Sara E. Patterson(9), Cara Statz(9), Theodorus W. J. Gadella(8), Susan M. Mockus(8), Jakobus van Unen(7), Kathleen J. Green(5), Niels Heemskerk(4), Jos van Rijssel(4), Stephan Huveneers(4), Jaap D. van Buul(4), Andrew P. Kowalczyk(4), Nathalie R. Reinhard(3), Ilse Timmerman(3), Jeffrey Kroon(3), Antje Schaefer(3), Mark Hoogenboezem(3), Michael L. Kerber(2), Damon T. Jacobs(2)