Niels Heemskerk

Netherlands Center for Occupational Diseases — Netherlands

Medicine · Health Sciences

11h-index691citations17works0.02yr avg
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Research Topics

Cell Adhesion Molecules Research(9), Protein Kinase Regulation and GTPase Signaling(4), Cellular Mechanics and Interactions(4), Hippo pathway signaling and YAP/TAZ(4), Angiogenesis and VEGF in Cancer(3)

Publications17 total

TNF-α x FcαRI bi-specific antibody potentiates neutrophil-mediated anti-tumor effects
Scientific Reports·2025Open Access
Anti-FcαRI Monoclonal Antibodies Resolve IgA Autoantibody-Mediated Disease
Frontiers in Immunology·2022· 11 citedOpen Access
EGFR-dependent tyrosine phosphorylation of integrin β4 is not required for downstream signaling events in cancer cell lines
Scientific Reports·2021· 8 citedOpen Access
Augmented antibody-based anticancer therapeutics boost neutrophil cytotoxicity
Journal of Clinical Investigation·2021· 58 citedOpen Access
A Window of Opportunity: Targeting Cancer Endothelium to Enhance Immunotherapy
Frontiers in Immunology·2020· 34 citedOpen Access
Spillage of bacterial products during colon surgery increases the risk of liver metastases development in a rat colon carcinoma model.
OncoImmunology·2018· 10 citedOpen Access
Monoclonal antibody‐mediated killing of tumour cells by neutrophils
European Journal of Clinical Investigation·2018· 44 citedOpen Access
Flow-induced endothelial cell alignment requires the RhoGEF Trio as a scaffold protein to polarize active Rac1 distribution
Molecular Biology of the Cell·2017· 42 citedOpen Access
Leukocyte trafficking and vascular integrity
Data Archiving and Networked Services (DANS)·2017Open Access
Leukocyte transendothelial migration: A local affair
Small GTPases·2016· 81 citedOpen Access
Annexin A2 Limits Neutrophil Transendothelial Migration by Organizing the Spatial Distribution of ICAM-1
The Journal of Immunology·2016· 15 citedOpen Access
F-actin-rich contractile endothelial pores prevent vascular leakage during leukocyte diapedesis through local RhoA signalling
Nature Communications·2016· 139 citedOpen Access
A local VE-cadherin and Trio-based signaling complex stabilizes endothelial junctions through Rac1
Journal of Cell Science·2015· 54 citedOpen Access
A local VE-cadherin and Trio-based signaling complex stabilizes endothelial junctions through Rac1
Development·2015· 8 cited
The Ins and Outs of Small GTPase Rac1 in the Vasculature
Journal of Pharmacology and Experimental Therapeutics·2015· 24 cited
A local VE-cadherin/Trio-based signaling complex stabilizes endothelial junctions through Rac1
Journal of Cell Science·2015· 97 citedOpen Access
Rho-GTPase signaling in leukocyte extravasation
Cell Adhesion & Migration·2014· 66 citedOpen Access

Frequent Co-authors

Jaap D. van Buul(9), Jos van Rijssel(7), Marjolein van Egmond(6), Taofei Yin(4), Jakobus van Unen(4), Stephan Huveneers(4), Joachim Goedhart(4), Yi Wu(4), Jeffrey Kroon(4), Ilse Timmerman(3), Antje Schaefer(3), Mark Hoogenboezem(3), Theodorus W. J. Gadella(3), Lilian Schimmel(2), Chantal Oort(2), Mandy Gruijs(2), Dennis Y. Gout(2), Paula J. Winter(2), Arthur E. H. Bentlage(2), Marijn Bögels(2)