Maria T. Bengoechea-Alonso

Hamad bin Khalifa University — QA

Medicine · Health Sciences

14h-index1.7kcitations25works1.02yr avg
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Research Topics

Cholesterol and Lipid Metabolism(10), Peroxisome Proliferator-Activated Receptors(7), Lipid metabolism and biosynthesis(7), Cancer, Lipids, and Metabolism(5), Ubiquitin and proteasome pathways(4)

Publications25 total

The Functional Interaction Between PRDM16 and the SREBP Pathway Controls Lipid Metabolism
International Journal of Molecular Sciences·2025Open Access
The Functional Interaction Between PRDM16 and the SREBP Pathway Controls Lipid Metabolism
Preprints.org·2025Open Access
Functional characterization of the SDR42E1 reveals its role in vitamin D biosynthesis
Heliyon·2024· 3 citedOpen Access
Control of TGFβ signalling by ubiquitination independent function of E3 ubiquitin ligase TRIP12
Cell Death and Disease·2023· 6 citedOpen Access
Loss of the Fbw7 tumor suppressor rewires cholesterol metabolism in cancer cells leading to activation of the PI3K-AKT signalling axis
Frontiers in Oncology·2022· 9 citedOpen Access
The SREBP-dependent regulation of cyclin D1 coordinates cell proliferation and lipid synthesis
Frontiers in Oncology·2022· 16 citedOpen Access
The phosphorylation-dependent regulation of nuclear SREBP1 during mitosis links lipid metabolism and cell growth
Cell Cycle·2016· 51 citedOpen Access
The phosphorylation-dependent regulation of nuclear SREBP1 during mitosis links lipid metabolism and cell growth
Figshare·2016Open Access
Fbw7 dimerization determines the specificity and robustness of substrate degradation
Genes & Development·2013· 98 citedOpen Access
TRAF6 ubiquitinates TGFβ type I receptor to promote its cleavage and nuclear translocation in cancer
Nature Communications·2011· 176 citedOpen Access
Tumor suppressor Fbxw7 regulates TGFβ signaling by targeting TGIF1 for degradation
Oncogene·2010· 47 cited
The ubiquitin ligase Fbxw7 controls adipocyte differentiation by targeting C/EBPα for degradation
Proceedings of the National Academy of Sciences·2010· 80 citedOpen Access
Quelling cholesterol pathway fends off brain damage
Nature Medicine·2009· 2 cited
A Phosphorylation Cascade Controls the Degradation of Active SREBP1
Journal of Biological Chemistry·2009· 146 citedOpen Access
Cdk1/cyclin B‐mediated phosphorylation regulates SREBP1
The FASEB Journal·2007· 1 cited
SREBP in signal transduction: cholesterol metabolism and beyond
Current Opinion in Cell Biology·2007· 275 cited
Cdk1/Cyclin B-Mediated Phosphorylation Stabilizes SREBP1 During Mitosis
Cell Cycle·2006· 59 citedOpen Access
Phosphorylation and Ubiquitination of the Transcription Factor Sterol Regulatory Element-binding Protein-1 in Response to DNA Binding
Journal of Biological Chemistry·2006· 132 citedOpen Access
Hyperphosphorylation regulates the activity of SREBP1 during mitosis
Proceedings of the National Academy of Sciences·2005· 61 citedOpen Access
Control of lipid metabolism by phosphorylation-dependent degradation of the SREBP family of transcription factors by SCFFbw7
Cell Metabolism·2005· 442 citedOpen Access
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Frequent Co-authors

Johan Ericsson(20), María J. López‐Zabalza(3), Esteban Santiago(3), Tanel Punga(2), N López-Moratalla(2), Arwa Aldaalis(2), Juan A. Osés-Prieto(2), Antonio Artigues(2), Ana Iriarte(2), Marino Martinez‐Carrion(2), Hafiz Majid Mahmood(2), Dana E. Al-Ansari(2), Khaled Machaca(2), Anders Sundqvist(1), Xin Ye(1), Vasyl Lukiyanchuk(1), Jianping Jin(1), J. Wade Harper(1), Yabing Mu(1), Reshma Sundar(1)