John H. Horner

University of Illinois Chicago — United States

Chemistry · Physical Sciences

36h-index3.3kcitations82works0.02yr avg
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Research Topics

Radical Photochemical Reactions(42), Photochemistry and Electron Transfer Studies(30), Free Radicals and Antioxidants(20), Metal-Catalyzed Oxygenation Mechanisms(18), Pharmacogenetics and Drug Metabolism(11)

Publications82 total

Tear Fluid Extracellular DNA: Diagnostic and Therapeutic Implications in Dry Eye Disease
Investigative Ophthalmology & Visual Science·2013· 47 citedOpen Access
Bioluminescent detection of peroxynitrite with a boronic acid-caged luciferin
Free Radical Biology and Medicine·2013· 41 citedOpen Access
Ocular Surface Extracellular DNA and Nuclease Activity Imbalance: A New Paradigm for Inflammation in Dry Eye Disease
Investigative Ophthalmology & Visual Science·2012· 118 citedOpen Access
Cytochrome P450 119 Compounds I Formed by Chemical Oxidation and Photooxidation Are the Same Species
Chemistry - A European Journal·2012· 6 cited
(ω‐2,ω‐2,ω‐3,ω‐3)‐Tetradeuterio‐fatty acids for mechanistic studies of enzyme‐catalyzed hydroxylation reactions
Journal of Labelled Compounds and Radiopharmaceuticals·2012· 5 cited
Rates of Fatty Acid Oxidations by P450 Compound I are pH Dependent
ChemBioChem·2012· 10 citedOpen Access
Rate‐Controlling Isomerizations in Fatty Acid Oxidations by a Cytochrome P450 Compound I
Chemistry - A European Journal·2012· 10 cited
Oxidation of 10-undecenoic acid by cytochrome P450BM-3 and its Compound I transient
Organic & Biomolecular Chemistry·2011· 10 cited
Rate constants for cyclizations of α-hydroxy radical clocks
Organic & Biomolecular Chemistry·2010· 6 cited
Low temperature photo-oxidation of chloroperoxidase Compound II
Journal of Inorganic Biochemistry·2010· 5 citedOpen Access
Compounds I by Photo-Oxidation of Compounds II
ECS Transactions·2009· 2 cited
Kinetics and Activation Parameters for Oxidations of Styrene by Compounds I from the Cytochrome P450<sub>BM-3</sub> (CYP102A1) Heme Domain and from CYP119
Biochemistry·2009· 24 citedOpen Access
Quantitative Production of Compound I from a Cytochrome P450 Enzyme at Low Temperatures. Kinetics, Activation Parameters, and Kinetic Isotope Effects for Oxidation of Benzyl Alcohol
Journal of the American Chemical Society·2009· 62 citedOpen Access
Kinetics of Oxidation of Benzphetamine by Compounds I of Cytochrome P450 2B4 and Its Mutants
Journal of the American Chemical Society·2009· 33 citedOpen Access
Highly Reactive Porphyrin−Iron−Oxo Derivatives Produced by Photolyses of Metastable Porphyrin−Iron(IV) Diperchlorates
Journal of the American Chemical Society·2009· 77 citedOpen Access
Spectra and Kinetic Studies of the Compound I Derivative of Cytochrome P450 119
Journal of the American Chemical Society·2008· 63 citedOpen Access
Tunneling in C−H Oxidation Reactions by an Oxoiron(IV) Porphyrin Radical Cation: Direct Measurements of Very Large H/D Kinetic Isotope Effects
Journal of the American Chemical Society·2008· 71 citedOpen Access
Rate Constants for 1,5- and 1,6-Hydrogen Atom Transfer Reactions of Mono-, Di-, and Tri-aryl-substituted Donors, Models for Hydrogen Atom Transfers in Polyunsaturated Fatty Acid Radicals
The Journal of Physical Chemistry A·2008· 24 cited
X-ray absorption spectroscopic characterization of a cytochrome P450 compound II derivative
Proceedings of the National Academy of Sciences·2008· 63 citedOpen Access
Kinetic Studies of a Fast, Reversible Alkene Radical Cation Cyclization Reaction
The Journal of Organic Chemistry·2007· 12 cited
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Frequent Co-authors

Martin Newcomb(48), Felix N. Martinez(7), Osama M. Musa(6), Xin Sheng(5), Christopher Tronche(4), Michael T. Blanda(3), Seung‐Yong Choi(3), Haifa Shahin(3), Qin Wang(3), David Crich(3), Xianhai Huang(3), Laurent Bagnol(3), R. Esala P. Chandrasena(2), James A. Halgrimson(2), Stephen G. Sligar(2), Anne Bouvier(2), Snehal Sonawane(2), Shweta Chaudhary(2), Sonal Gandhi(2), Sapna Tibrewal(2)