Shannon L. Flaugh

Iowa State University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

7h-index732citations14works0.02yr avg
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Research Topics

Connexins and lens biology(10), Heat shock proteins research(9), Enzyme Structure and Function(6), Protein Structure and Dynamics(2), Advanced Glycation End Products research(2)

Publications14 total

Folding and stability of the isolated Greek key domains of the long‐lived human lens proteins γD‐crystallin and γS‐crystallin
Protein Science·2007· 111 citedOpen Access
Mechanism of Fluorescence Quenching of Tryptophans in Human S-Crystallin
Investigative Ophthalmology & Visual Science·2007
Stability and aggregation differences in two lens γ‐crystallins, proteins implicated in cataract
The FASEB Journal·2007
Human alpha‐crystallin chaperone suppresses the aggregation of partially folded intermediates of human gamma D‐crystallin and its deamidated forms.
The FASEB Journal·2007
Mechanism of the Highly Efficient Quenching of Tryptophan Fluorescence in Human γD-Crystallin
Biochemistry·2006· 92 cited
Glutamine Deamidation Destabilizes Human γD-Crystallin and Lowers the Kinetic Barrier to Unfolding
Journal of Biological Chemistry·2006· 121 citedOpen Access
Folding, stability and aggregation of the long-lived eye lens protein human gamma D crystallin
DSpace@MIT (Massachusetts Institute of Technology)·2006· 1 citedOpen Access
Interdomain side‐chain interactions in human γD crystallin influencing folding and stability
Protein Science·2005· 107 citedOpen Access
The Effects of Deamidation on the Stability and Aggregation of Human D Crystallin
2005
Engineering Protein Chimeras of Human D and Human S Crystallin to Identify Sequence Components Involved in vitro Aggregation of Human D Crystallin
Investigative Ophthalmology & Visual Science·2005
Contributions of hydrophobic domain interface interactions to the folding and stability of human γD‐crystallin
Protein Science·2005· 103 citedOpen Access
Probing folding and fluorescence quenching in human γD crystallin Greek key domains using triple tryptophan mutant proteins
Protein Science·2004· 104 citedOpen Access
The Role of the Domain Interface of Human gammaD Crystallin in Folding, Stability and Fibril Formation
2004
Effects of Macromolecular Crowding on the Intrinsically Disordered Proteins c-Fos and p27<sup>Kip1</sup>
Biomacromolecules·2001· 93 cited

Frequent Co-authors

Jonathan King(8), Melissa S. Kosinski‐Collins(6), Jonathan A. King(4), Ishara A. Mills(3), Patrik R. Callis(2), Ira Mills(2), Kevin J. Lumb(1), Jiejin Chen(1), J. Chen(1), Ligia Isabel Acosta Sampson(1), Ishara Mills(1)