Alexandra M. Ortiz

National Institutes of Health — United States

Immunology and Microbiology · Life Sciences

18h-index1.7kcitations55works3.12yr avg
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Research Topics

HIV Research and Treatment(32), Immune Cell Function and Interaction(18), Gut microbiota and health(16), HIV/AIDS Research and Interventions(11), T-cell and B-cell Immunology(8)

Publications55 total

Oropouche virus efficiently replicates and is immunostimulatory in vivo in nonhuman primate species
Science Advances·2025· 3 citedOpen Access
Repeated enema administration in rhesus macaques is not sufficient to promote bacterial dysbiosis or gastrointestinal dysfunction
Mucosal Immunology·2025
SARS-CoV-2 infection perturbs the gastrointestinal tract and induces modest microbial translocation across the intestinal barrier
Journal of Virology·2024· 8 citedOpen Access
Translocating bacteria in SIV infection are not stochastic and preferentially express cytosine methyltransferases
Mucosal Immunology·2024· 2 citedOpen Access
Untangling the role of the microbiome across the stages of HIV disease
Current Opinion in HIV and AIDS·2024· 4 citedOpen Access
Immunotoxin-mediated depletion of Gag-specific CD8+ T cells undermines natural control of SIV
JCI Insight·2024· 3 citedOpen Access
SIV infection and ARV treatment reshape the transcriptional and epigenetic profile of naïve and memory T cells <i>in vivo</i>
Journal of Virology·2024· 2 citedOpen Access
2-Hydroxypropyl-β-Cyclodextrin Treatment Induces Modest Immune Activation in Healthy Rhesus Macaques
Journal of Virology·2023· 1 citedOpen Access
Correction: Mitigation of endemic GI-tract pathogen-mediated inflammation through development of multimodal treatment regimen and its impact on SIV acquisition in rhesus macaques
PLoS Pathogens·2023Open Access
Experimental bacterial dysbiosis with consequent immune alterations increase intrarectal SIV acquisition susceptibility
Cell Reports·2023· 9 citedOpen Access
Host Genetics and Environment Shape the Composition of the Gastrointestinal Microbiome in Nonhuman Primates
Microbiology Spectrum·2022· 12 citedOpen Access
Multiple modes of antigen exposure induce clonotypically diverse epitope-specific CD8+ T cells across multiple tissues in nonhuman primates
PLoS Pathogens·2022· 6 citedOpen Access
Butyrate administration is not sufficient to improve immune reconstitution in antiretroviral-treated SIV-infected macaques
Scientific Reports·2022· 15 citedOpen Access
The Vaginal Microbiome of Nonhuman Primates Can Be Only Transiently Altered to Become <i>Lactobacillus</i> Dominant without Reducing Inflammation
Microbiology Spectrum·2021· 19 citedOpen Access
Microbiome Studies in Non-human Primates
Current HIV/AIDS Reports·2021· 13 citedOpen Access
Mitigation of endemic GI-tract pathogen-mediated inflammation through development of multimodal treatment regimen and its impact on SIV acquisition in rhesus macaques
PLoS Pathogens·2021· 13 citedOpen Access
Luminal microvesicles uniquely influence translocating bacteria after SIV infection
Mucosal Immunology·2021· 3 citedOpen Access
Corrigendum to: Impact of Acute HIV Infection and Early Antiretroviral Therapy on the Human Gut Microbiome
Open Forum Infectious Diseases·2020Open Access
Biomarkers of Cellular Stress Do Not Associate with sCD14 in Progressive HIV and SIV Infections in Vivo
Pathogens and Immunity·2020· 7 citedOpen Access
Simian Immunodeficiency Virus Infection of Rhesus Macaques Results in Delayed Zika Virus Clearance
mBio·2019· 8 citedOpen Access
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Frequent Co-authors

Jason M. Brenchley(37), Jacob K. Flynn(13), Carol L. Vinton(12), Mirko Paiardini(10), Guido Silvestri(10), Carly E. Starke(8), Joseph C. Mudd(7), Yasmine Belkaid(6), Ronald G. Collman(6), Jacob D. Estes(6), Charlotte A. Langner(6), Miles P. Davenport(5), Claire Deléage(5), Vanessa M. Hirsch(5), Jennifer Simpson(5), Kelsie Brooks(5), Andrew R. Rahmberg(5), Luca Micci(4), Nicholas Francella(4), Cristian Apetrei(4)