K. Mark Coggeshall

Oklahoma Medical Research Foundation — United States

Medicine · Health Sciences

53h-index9.0kcitations132works0.02yr avg
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Research Topics

Monoclonal and Polyclonal Antibodies Research(26), T-cell and B-cell Immunology(25), Protein Kinase Regulation and GTPase Signaling(24), Bacillus and Francisella bacterial research(21), Cell Adhesion Molecules Research(15)

Publications132 total

Monocyte uptake of polymeric peptidoglycan is bimodal and governed by complement C3 and C4 opsonins
JCI Insight·2024Open Access
Immune Proteolytic Cascades
Elsevier eBooks·2024
Gram-Positive Bacteria Cell Wall Peptidoglycan Polymers Activate Human Dendritic Cells to Produce IL-23 and IL-1β and Promote TH17 Cell Differentiation
Microorganisms·2023· 13 citedOpen Access
Internalization of Polymeric Bacterial Peptidoglycan Occurs through Either Actin or Dynamin Dependent Pathways
Microorganisms·2022· 5 citedOpen Access
Complement C5 inhibition protects against hemolytic anemia and acute kidney injury in anthrax peptidoglycan-induced sepsis in baboons
Proceedings of the National Academy of Sciences·2021· 18 citedOpen Access
C3 Opsonization of Anthrax Bacterium and Peptidoglycan Supports Recognition and Activation of Neutrophils
Microorganisms·2020· 7 citedOpen Access
Monocyte procoagulant responses to anthrax peptidoglycan are reinforced by proinflammatory cytokine signaling
Blood Advances·2019· 13 citedOpen Access
Peptidoglycan induces disseminated intravascular coagulation in baboons through activation of both coagulation pathways
Blood·2018· 37 citedOpen Access
Gene expression profiling of primary human type I alveolar epithelial cells exposed to Bacillus anthracis spores reveals induction of neutrophil and monocyte chemokines
Microbial Pathogenesis·2018· 4 citedOpen Access
Serum Amyloid P and IgG Exhibit Differential Capabilities in the Activation of the Innate Immune System in Response to Bacillus anthracis Peptidoglycan
Infection and Immunity·2018· 12 citedOpen Access
Neither Lys- and DAP-type peptidoglycans stimulate mouse or human innate immune cells via Toll-like receptor 2
PLoS ONE·2018· 14 citedOpen Access
Mechanisms of Transmembrane Signal Transduction During B Cell Activation
2018· 1 cited
Inhibition of complement C5 protects against organ failure and reduces mortality in a baboon model of <i>Escherichia coli</i> sepsis
Proceedings of the National Academy of Sciences·2017· 106 citedOpen Access
Hexokinase Is an Innate Immune Receptor for the Detection of Bacterial Peptidoglycan
Cell·2016· 544 citedOpen Access
Bacillus anthracis spore movement does not require a carrier cell and is not affected by lethal toxin in human lung models
Microbes and Infection·2016· 11 citedOpen Access
Proteolytic Cascades
Elsevier eBooks·2016
Interleukin‐6 Deficiency Corrects Nephritis, Lymphocyte Abnormalities, and Secondary Sjögren's Syndrome Features in Lupus‐Prone <i>Sle1.Yaa</i> Mice
Arthritis & Rheumatology·2014· 31 citedOpen Access
Crosstalk between the coagulation and complement systems in sepsis
Thrombosis Research·2014· 148 citedOpen Access
Human SAP Is a Novel Peptidoglycan Recognition Protein That Induces Complement-Independent Phagocytosis of <i>Staphylococcus aureus</i>
The Journal of Immunology·2013· 22 citedOpen Access
Toxin Inhibition of Antimicrobial Factors Induced by Bacillus anthracis Peptidoglycan in Human Blood
Infection and Immunity·2013· 7 citedOpen Access
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Frequent Co-authors

Amnon Altman(9), Susheela Tridandapani(8), Gottfried Baier(7), Damon S. Cooney(6), Erich Gulbins(5), John C. Cambier(5), George Chacko(4), Clark L. Anderson(4), Hyewon Phee(4), Anand Jacob(4), Tomas Mustelin(3), Noah Isakov(3), David Telford(3), Kenichiro Maeda(3), Birgit Brenner(3), E. Gulbins(3), Klaus Schlottmann(3), Florian Läng(3), Nathalie Bonnefoy(3), Todd W. Kelley(3)