Erich Gulbins

University of Duisburg-Essen — Germany

Biochemistry, Genetics and Molecular Biology · Life Sciences

97h-index35.0kcitations573works3.12yr avg
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Research Topics

Sphingolipid Metabolism and Signaling(242), Lipid Membrane Structure and Behavior(117), Erythrocyte Function and Pathophysiology(79), Cystic Fibrosis Research Advances(60), Ion channel regulation and function(50)

Publications571 total

Maraviroc attenuates orbital remodeling, inflammation, and lipid dysregulation in a murine model of thyroid eye disease associated with Graves’ disease
Frontiers in Endocrinology·2026Open Access
Tumor-specific targeting of a mitochondrial Kv1.3 channel inhibitor through conjugation to gastrin/cholecystokinin B receptor ligand strongly reduces pancreatic ductal adenocarcinoma in orthotopic models
Pharmacological Research·2026Open Access
Immune activation and response dynamics of human <scp>iPSC</scp> ‐derived macrophages in tuberculosis infection models
Clinical & Translational Immunology·2026Open Access
Acid ceramidase regulates CD8+ T-cell exhaustion via type I interferon-mediated upregulation of PD-L1
Frontiers in Immunology·2025Open Access
Deactivation of ceramide de novo synthesis induces cerebral angiogenesis and microvascular remodeling post-ischemia/reperfusion in mice via mechanisms not predominated by extracellular vesicles
Journal of Cerebral Blood Flow & Metabolism·2025Open Access
Selective inhibition of mitochondrial Kv1.3 prevents and alleviates multiple sclerosis in vivo
EMBO Molecular Medicine·2025· 2 citedOpen Access
Amitriptyline potently neutralizes distinct SARS-CoV-2 variants including D614G, Omicron BA.5, and Omicron XBB.1
Frontiers in Microbiology·2025· 1 citedOpen Access
Amitriptyline inhibits Plasmodium development in infected red blood cells by modulating sphingolipid metabolism and glucose uptake
Biomedicine & Pharmacotherapy·2025· 2 citedOpen Access
Sphingosine kills Mycobacteria and suppresses mycobacterial lung infections
Journal of Molecular Medicine·2025· 1 citedOpen Access
Sphingosine-mediated death of <i>Pseudomonas aeruginosa</i> involves degradation of cardiolipin by the maintenance of outer lipid asymmetry system
Infection and Immunity·2025· 1 citedOpen Access
Brain acid sphingomyelinase controls addiction-related behaviours in a sex-specific way
Neurobiology of Disease·2025· 3 citedOpen Access
Acid sphingomyelinase activity suggests a new antipsychotic pharmaco-treatment strategy for schizophrenia
Molecular Psychiatry·2025· 11 citedOpen Access
Acid ceramidase of macrophages traps herpes simplex virus in multivesicular bodies and protects from severe disease
Zeitschrift für Gastroenterologie·2025Open Access
Acid Sphingomyelinase Activation and ROS Generation Potentiate Antiproliferative Effects of Mitomycin in HCC
International Journal of Molecular Sciences·2024· 1 citedOpen Access
Lipid signaling: facets of a versatile cell communication strategy in health and disease
Pflügers Archiv - European Journal of Physiology·2024Open Access
Phosphatidic acid is involved in regulation of autophagy in neurons in vitro and in vivo
Pflügers Archiv - European Journal of Physiology·2024· 3 citedOpen Access
Signaling roles of sphingolipids in the ischemic brain and their potential utility as therapeutic targets
Neurobiology of Disease·2024· 12 citedOpen Access
BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway
Science Advances·2024· 15 citedOpen Access
Acid sphingomyelinase inhibition induces cerebral angiogenesis post-ischemia/reperfusion in an oxidative stress-dependent way and promotes endothelial survival by regulating mitochondrial metabolism
Cell Death and Disease·2024· 11 citedOpen Access
Sphingosine is involved in PAPTP-induced death of pancreas cancer cells by interfering with mitochondrial functions
Journal of Molecular Medicine·2024· 3 citedOpen Access
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Frequent Co-authors

Florian Läng(19), Heike Grassmé(13), Ildikò Szabó(9), Johannes Kornhuber(8), Philipp A. Lang(6), Martin Reichel(6), Katrin Anne Becker(6), Andrea Riehle(5), Richard Kolesnick(5), Barbara Wilker(5), Michael Weller(5), Stephan M. Huber(5), Mario Zoratti(5), Christian P. Müller(4), Philipp Tripal(4), Burkhard Kleuser(4), Michael Föller(4), Jürgen Bock(4), Matthias Soddemann(4), Constantin Adams(3)