David R. Barn

NHS Lanarkshire — United Kingdom

Neuroscience · Life Sciences

6h-index163citations8works0.02yr avg
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Research Topics

Neuropeptides and Animal Physiology(3), Receptor Mechanisms and Signaling(3), Pharmacological Receptor Mechanisms and Effects(3), Chemical Synthesis and Analysis(2), Neurotransmitter Receptor Influence on Behavior(1)

Publications8 total

Optimisation of pharmacokinetic properties to afford an orally bioavailable and selective V1A receptor antagonist
Bioorganic & Medicinal Chemistry Letters·2011· 3 citedOpen Access
The discovery of novel 8-azabicyclo[3.2.1]octan-3-yl)-3-(4-chlorophenyl) propanamides as vasopressin V1A receptor antagonists
Bioorganic & Medicinal Chemistry Letters·2011· 8 citedOpen Access
The discovery of novel indole-2-carboxamides as cannabinoid CB1 receptor antagonists
Bioorganic & Medicinal Chemistry Letters·2010· 6 cited
Synthesis and SAR studies of 3-phenoxypropyl piperidine analogues as ORL1 (NOP) receptor agonists
Bioorganic & Medicinal Chemistry Letters·2004· 12 citedOpen Access
Design and Synthesis of a Maximally Diverse and Druglike Screening Library Using REM Resin Methodology
Journal of Combinatorial Chemistry·2001· 18 cited
Parallel synthesis and biological activity of a new class of high affinity and selective δ-opioid ligand
Bioorganic & Medicinal Chemistry·2001· 21 cited
Synthesis of novel analogues of the delta opioid ligand SNC-80 using AlCl3-promoted aminolysis
Bioorganic & Medicinal Chemistry Letters·1999· 22 citedOpen Access
Synthesis of an array of amides by aluminium chloride assisted cleavage of resin-bound esters
Tetrahedron Letters·1996· 73 cited

Frequent Co-authors

J. Richard Morphy(4), Richard Goodwin(4), Grant Wishart(4), Jean E. Cottney(3), Wilson Caulfield(3), James Α. Baker(3), Kirsteen Buchanan(3), Zoran Ranković(2), Ronald Palin(2), John K. Clark(2), Phillip M. Cowley(2), Susan Napier(2), W. Arbuckle(2), Matilda Bingham(2), Angus R. Brown(2), Mark Craighead(2), Susan Goutcher(2), Rachel Milne(2), Chris Mort(2), Jeremy Presland(2)