Colette Chaney

Fred Hutch Cancer Center — United States

Medicine · Health Sciences

14h-index4.2kcitations23works0.02yr avg
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Research Topics

CAR-T cell therapy research(19), Hematopoietic Stem Cell Transplantation(5), T-cell and B-cell Immunology(3), Immunotherapy and Immune Responses(3), Virus-based gene therapy research(3)

Publications23 total

Phase I Study of Adoptive Immunotherapy with HA-1-Specific CD8+ and CD4+ Memory T Cells for Children and Adults with Relapsed Acute Leukemia after Allogeneic Hematopoietic Stem Cell Transplantation (HCT): Trial in Progress
Blood·2020· 6 cited
Building and Sailing the Ship Simultaneously: A Programmatic Ecosystem for Cellular Based Therapies
Biology of Blood and Marrow Transplantation·2020
Abstract CT131: A phase I study of adoptive immunotherapy for advanced ROR1+ malignancies with defined subsets of autologous T cells expressing a ROR1-specific chimeric antigen receptor (ROR1-CAR)
Cancer Research·2018· 17 cited
Phase I study of immunotherapy for advanced ROR1+ malignancies with autologous ROR1-specific chimeric antigen receptor-modified (CAR)-T cells.
Journal of Clinical Oncology·2018· 33 cited
Biomarkers of Cytokine Release Syndrome and Neurotoxicity after CD19 CAR-T Cells and Mitigation of Toxicity By Cell Dose
Blood·2016· 10 cited
CD19 CAR-T Cells Are Highly Effective in Ibrutinib-Refractory Chronic Lymphocytic Leukemia
Blood·2016· 15 cited
Immunotherapy of non-Hodgkin’s lymphoma with a defined ratio of CD8 <sup>+</sup> and CD4 <sup>+</sup> CD19-specific chimeric antigen receptor–modified T cells
Science Translational Medicine·2016· 989 cited
Rate of durable complete response in ALL, NHL, and CLL after immunotherapy with optimized lymphodepletion and defined composition CD19 CAR-T cells.
Journal of Clinical Oncology·2016· 24 cited
CD19 CAR–T cells of defined CD4+:CD8+ composition in adult B cell ALL patients
Journal of Clinical Investigation·2016· 2.1k citedOpen Access
in adult B cell ALL patients
2016
Anti-CD19 Chimeric Antigen Receptor-Modified T Cell Therapy for B Cell Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia: Fludarabine and Cyclophosphamide Lymphodepletion Improves In Vivo Expansion and Persistence of CAR-T Cells and Clinical Outcomes
Blood·2015· 70 cited
Addition of Fludarabine to Cyclophosphamide Lymphodepletion Improves In Vivo Expansion of CD19 Chimeric Antigen Receptor-Modified T Cells and Clinical Outcome in Adults with B Cell Acute Lymphoblastic Leukemia
Blood·2015· 54 cited
Outcomes of acute leukemia patients transplanted with naive T cell–depleted stem cell grafts
Journal of Clinical Investigation·2015· 266 citedOpen Access
Immunotherapy with CD19-specific chimeric antigen receptor (CAR)-modified T cells of defined subset composition.
Journal of Clinical Oncology·2015· 15 cited
Therapy of B Cell Malignancies with CD19-Specific Chimeric Antigen Receptor-Modified T Cells of Defined Subset Composition
Blood·2014· 17 cited
Transferred Donor-Derived Virus Specific CD8+ T Cells That Have Been Transduced to Express a WT1-Specific T Cell Receptor Can Persist and Provide Anti-Leukemic Activity in AML Patients Post-Transplant
Blood·2014· 10 cited
Transferred WT1-Reactive CD8 <sup>+</sup> T Cells Can Mediate Antileukemic Activity and Persist in Post-Transplant Patients
Science Translational Medicine·2013· 306 cited
Depletion of Naïve T Cells From Peripheral Blood Stem Cell Grafts for GVHD Prevention
Biology of Blood and Marrow Transplantation·2013· 3 citedOpen Access
Transferred Donor-Derived WT1-Specific CD8+ T-Cell Clones After Hematopoietic Cell Transplantation Mediate Antileukemic Activity and Can Establish Persistent Responses without Toxicity to Normal Tissues in High-Risk Leukemia Patients
Blood·2012
Leukemia-associated minor histocompatibility antigen discovery using T-cell clones isolated by in vitro stimulation of naive CD8+ T cells
Blood·2010· 99 citedOpen Access
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Frequent Co-authors

Stanley R. Riddell(16), Cameron J. Turtle(14), Shelly Heimfeld(13), David G. Maloney(13), Carolina Berger(10), Laïla‐Aïcha Hanafi(8), Sindhu Cherian(7), Daniel Sommermeyer(7), Xueyan Chen(7), Brent L. Wood(7), Michael Hudecek(6), Barbara Pender(6), Tanya M Budiarto(6), Natalia N Steevens(6), Michael C. Jensen(6), Katherine M. Melville(5), Emily Robinson(5), Lorinda Soma(5), Marie Bleakley(5), Ted Gooley(5)