Michael R. Betts

University of Pennsylvania — United States

Immunology and Microbiology · Life Sciences

85h-index31.3kcitations292works1.82yr avg
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Research Topics

Immune Cell Function and Interaction(138), HIV Research and Treatment(111), T-cell and B-cell Immunology(92), Immunotherapy and Immune Responses(52), Cytomegalovirus and herpesvirus research(29)

Publications290 total

Clinical trial results provide the rationale to protect dual HIV-specific T cells with a signaling-defective HIV fusion inhibitor
Molecular Therapy·2026
Single-cell characterization of the gastrointestinal HIV reservoir reveals heterogeneous cellular phenotypes
Journal of Clinical Investigation·2025Open Access
Selective infection and loss of PRDM1+ LN Tfh cells in uncontrolled HIV infection precludes formation of Tfh reservoirs under ART
2025Open Access
Dysregulated lymphocyte localization in idiopathic multicentric Castleman disease
2025· 1 citedOpen Access
Decoding the immune cells in the fetal brain at murine mid-gestation 4687
The Journal of Immunology·2025Open Access
Fractalkine-conjugated mRNA LNPs induce expression of homing molecules in cytotoxic effector CD8+ T cells 4515
The Journal of Immunology·2025Open Access
Investigating the immunological effect of MYCN depletion in MYCN-amplified neuroblastoma 9167
The Journal of Immunology·2025Open Access
In vivo reprogramming of cytotoxic effector CD8 <sup>+</sup> T cells via fractalkine-conjugated mRNA-LNP
2025Open Access
Transient tissue residency and lymphatic egress define human CD56bright NK cell homeostasis
Nature Immunology·2025· 2 citedOpen Access
Therapeutic CD8 <sup>+</sup> T cell tissue retention and immunomodulation during ART interruption fail to prevent SIV rebound
Proceedings of the National Academy of Sciences·2025· 3 citedOpen Access
Spatial transcriptomics from pancreas and local draining lymph node tissue reveals a lymphotoxin-β signature in human type 1 diabetes
2025Open Access
Immune perturbations in human pancreas lymphatic tissues prior to and after type 1 diabetes onset
Nature Communications·2025· 7 citedOpen Access
Abstract 482: Development of a CD3-targeted lentiviral vector compatible with M. <i>nemestrina</i> to evaluate in vivo CAR-T gene therapy
Cancer Research·2025
Therapeutic CD8+T cell tissue retention and immunomodulation during ART interruption fails to prevent SIV rebound
2025Open Access
The XCL1/XCR1 axis is upregulated in type 1 diabetes and aggravates its pathogenesis
JCI Insight·2025Open Access
Response to Comment on Manduchi et al. No Evidence for Persistent Enteroviral B Infection of Pancreatic Islets in Patients With Type 1 Diabetes and Prediabetes From RNA Sequencing Data. Diabetes 2024;73:1697–1704
Diabetes·2025Open Access
Immunologic and inflammatory consequences of SARS-CoV-2 infection and its implications in renal disease
Frontiers in Immunology·2025· 8 citedOpen Access
Trafficking, Not Lymphoproliferation, Promotes Lymphadenopathy in Idiopathic Multicentric Castleman Disease
Blood·2024· 1 citedOpen Access
Erratum to: Progress Note 2024: Curing HIV; Not in My Lifetime or Just Around the Corner?
UNC Libraries·2024Open Access
Progress Note 2024: Curing HIV; Not in My Lifetime or Just Around the Corner?
UNC Libraries·2024Open Access
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Frequent Co-authors

Richard A. Koup(20), Daniel C. Douek(14), E. John Wherry(13), Leticia Kuri-Cervantes(10), Jason M. Brenchley(10), David A. Price(10), Scott E. Hensley(9), Mario Roederer(9), Joseph P. Casazza(9), Divij Mathew(8), Allison R. Greenplate(8), Sigrid Gouma(8), Sokratis A. Apostolidis(8), Brenna J. Hill(8), Josephine R. Giles(7), Amy E. Baxter(7), Oliva Kuthuru(7), Ajinkya Pattekar(7), Madison E. Weirick(7), Laura A. Vella(7)