Phaethon Philbrook

Louisiana State University Health Sciences Center New Orleans — United States

Immunology and Microbiology · Life Sciences

10h-index1.3kcitations16works0.72yr avg
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Research Topics

Immune Cell Function and Interaction(5), Adenosine and Purinergic Signaling(4), Immune cells in cancer(3), Immunotherapy and Immune Responses(2), Cancer, Hypoxia, and Metabolism(2)

Publications16 total

Medium-Chain Fatty Acid Receptor GPR84 Modulates Cytotoxic CD8 T-cell Antitumor Immunity through Metabolic Reprogramming
Cancer Immunology Research·2026Open Access
Excess Potassium Promotes Autophagy to Maintain the Immunosuppressive Capacity of Myeloid-Derived Suppressor Cells Independent of Arginase 1
Cells·2024· 1 citedOpen Access
Differential Diagnosis of Leptomeningeal Enhancement in the Pediatric Population (P4-4.010)
Neurology·2024· 1 cited
Novel Biodistribution of PSMA Radiotracer in the Uvula of Patients Undergoing PSMA PET/CT
Clinical Nuclear Medicine·2023
Abstract 2081: Poly ADP-ribose polymerase inhibition enhances T cell cytotoxicity and anti-tumor function by altering NAD+ levels
Cancer Research·2022· 1 cited
Severe COVID-19 Is Characterized by an Impaired Type I Interferon Response and Elevated Levels of Arginase Producing Granulocytic Myeloid Derived Suppressor Cells
Frontiers in Immunology·2021· 74 citedOpen Access
Transcriptome and Functions of Granulocytic Myeloid-Derived Suppressor Cells Determine their Association with Disease Severity of COVID-19
2021· 13 citedOpen Access
Targeted Elimination of Immunodominant B Cells Drives the Germinal Center Reaction toward Subdominant Epitopes
Cell Reports·2017· 31 citedOpen Access
Hypoxia and hypoxia-inducible factor (HIF) downregulate antigen-presenting MHC class I molecules limiting tumor cell recognition by T cells
PLoS ONE·2017· 116 citedOpen Access
Fluorinated Adenosine A<sub>2A</sub> Receptor Antagonists Inspired by Preladenant as Potential Cancer Immunotherapeutics
International Journal of Medicinal Chemistry·2017· 11 citedOpen Access
The GS Protein-coupled A2a Adenosine Receptor Controls T Cell Help in the Germinal Center
Journal of Biological Chemistry·2017· 31 citedOpen Access
Germinal Center Hypoxia Potentiates Immunoglobulin Class Switch Recombination
The Journal of Immunology·2016· 114 citedOpen Access
Immunological mechanisms of the antitumor effects of supplemental oxygenation
Science Translational Medicine·2015· 579 cited
Systemic oxygenation weakens the hypoxia and hypoxia inducible factor 1α-dependent and extracellular adenosine-mediated tumor protection
Journal of Molecular Medicine·2014· 195 citedOpen Access
Abstract 5080: Inhibiting the ALK1/BMP9 signaling pathway with dalantercept as an antiangiogenic therapy.
Cancer Research·2013· 3 cited
Yoga and Mindfulness as Therapeutic Interventions for Stroke Rehabilitation: A Systematic Review
Evidence-based Complementary and Alternative Medicine·2013· 90 citedOpen Access

Frequent Co-authors

Stephen Hatfield(7), Michail V. Sitkovsky(7), Robert Abbott(5), Shalini Sethumadhavan(5), Molly Thayer(4), Murillo Silva(4), Matthew J. Dean(4), Akio Ohta(3), Maria Dulfary Sanchez‐Pino(3), Luis Del Valle(3), Dorota Wyczechowska(3), Augusto C. Ochoa(3), Ramesh Thylur Puttalingaiah(3), Jørgen Kjaergäard(2), Dmitriy Lukashev(2), Taylor H. Schreiber(2), Bryan Belikoff(2), Scott J. Rodig(2), Jeffrey L. Kutok(2), Edwin K. Jackson(2)