Ruben van Boxtel

Oncode Institute — Netherlands

Biochemistry, Genetics and Molecular Biology · Life Sciences

46h-index18.0kcitations206works3.92yr avg
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Research Topics

Cancer Genomics and Diagnostics(74), Acute Myeloid Leukemia Research(40), Acute Lymphoblastic Leukemia research(31), CRISPR and Genetic Engineering(25), Cancer Research and Treatments(22)

Publications206 total

Single-cell whole-genome sequencing reveals convergent evolution in Burkitt lymphoma
2025
Posttransplantation clonal dynamics of hematopoietic stem cells carrying prenatal and early‐life <i>DNMT3A</i> mutations
HemaSphere·2025Open Access
GENETIC ORIGINS AND CLONAL TRAJECTORIES OF MONOSOMY 7 IN PEDIATRIC MDS
EJC Paediatric Oncology·2025Open Access
Tracing the evolution of clonal T cell responses in LGL leukemia with single-cell whole genome sequencing
Blood·2025Open Access
Small round cell sarcoma tumoroid biobank reveals CIC::DUX4 sarcoma vulnerability to MCL-1 inhibition
Nature Communications·2025· 4 citedOpen Access
Direct detection of 8-oxo-dG using nanopore sequencing
Nature Communications·2025· 8 citedOpen Access
Unraveling mutagenic processes influencing the tumor mutational patterns of individuals with constitutional mismatch repair deficiency
Nature Communications·2025· 4 citedOpen Access
Tables S1-3 from Prenatal Exposure to Chemotherapy Increases the Mutation Burden in Human Neonatal Hematopoietic Stem Cells
2025Open Access
Data from Prenatal Exposure to Chemotherapy Increases the Mutation Burden in Human Neonatal Hematopoietic Stem Cells
2025Open Access
Figure S4 from Prenatal Exposure to Chemotherapy Increases the Mutation Burden in Human Neonatal Hematopoietic Stem Cells
2025Open Access
Figure S1 from Prenatal Exposure to Chemotherapy Increases the Mutation Burden in Human Neonatal Hematopoietic Stem Cells
2025Open Access
Figure S5 from Prenatal Exposure to Chemotherapy Increases the Mutation Burden in Human Neonatal Hematopoietic Stem Cells
2025Open Access
Figure S3 from Prenatal Exposure to Chemotherapy Increases the Mutation Burden in Human Neonatal Hematopoietic Stem Cells
2025Open Access
Figure S2 from Prenatal Exposure to Chemotherapy Increases the Mutation Burden in Human Neonatal Hematopoietic Stem Cells
2025Open Access
Abstract 7488: Prenatal exposure to chemotherapy increases the mutation burden in human neonatal hematopoietic stem cells
Cancer Research·2025
Supplementary Figures 1-9 from Predisposition Footprints in the Somatic Genome of Wilms Tumors
2025Open Access
Data from Predisposition Footprints in the Somatic Genome of Wilms Tumors
2025Open Access
Supplementary Tables 1-8 from Predisposition Footprints in the Somatic Genome of Wilms Tumors
2025Open Access
Prenatal Exposure to Chemotherapy Increases the Mutation Burden in Human Neonatal Hematopoietic Stem Cells
Cancer Discovery·2025· 1 citedOpen Access
Protocol for genome-wide analysis of somatic variants at single-cell resolution using primary template-directed DNA amplification
STAR Protocols·2024· 2 citedOpen Access
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Frequent Co-authors

Edwin Cuppen(24), Hans Clevers(21), Rurika Oka(12), Francis Blokzijl(9), Harry Begthel(8), Michal Mokrý(8), Joep de Ligt(7), Jarno Drost(7), Meritxell Huch(6), Myrthe Jager(5), Arne van Hoeck(5), Monique M.A. Verstegen(5), Marc van de Wetering(5), Edward E. S. Nieuwenhuis(5), Luc J. W. van der Laan(5), Sander Boymans(5), Frank C. P. Holstege(5), Sylvia F. Boj(4), Isaäc J. Nijman(4), Jeroen Korving(4)