Deniz Dalkara

Centre National de la Recherche Scientifique — France

Biochemistry, Genetics and Molecular Biology · Life Sciences

50h-index8.2kcitations203works1.32yr avg
OpenAlex↗ORCID↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Retinal Development and Disorders(117), Photoreceptor and optogenetics research(59), Virus-based gene therapy research(46), Neuroscience and Neural Engineering(35), CRISPR and Genetic Engineering(34)

Publications203 total

AAV-delivered CRISPR-Cas9 elicits persistent retinal immune responses compared with transient responses to RNP
2025
Retinal organoids mirror CRISPR-Cas9 gene editing efficiency observed in vivo
Molecular Therapy — Methods & Clinical Development·2025· 1 citedOpen Access
The Rod Bipolar Cell Pathway Contributes To Surround Responses In OFF Retinal Ganglion Cells
2025Open Access
Photoactivated adenylyl cyclase in cortical astrocytes promotes synaptic potentiation and reveals alterations in Huntington’s disease
iScience·2025· 1 citedOpen Access
Ectopic expression of two cone opsins in mouse RGCs results in opposite responses to light stimulation, likely due to differential G protein activation
2025Open Access
Optimal sequencing depth for measuring the concentrations of molecular barcodes
Nucleic Acids Research·2025Open Access
Édition génique par transfert de complexes ribonucléoprotéiques de CRISPR/Cas9 dans la rétine
Springer Link (Chiba Institute of Technology)·2025
Inter-individual variability in immune responses to AAV-mediated ocular gene delivery across species impedes reliable immunomonitoring profile
2025· 1 citedOpen Access
Édition génique par transfert de complexes ribonucléoprotéiques de CRISPR/Cas9 dans la rétine
médecine/sciences·2025Open Access
CRISPR/Cas9 gene editing for the retina: transient delivery using RNP in vivo and development of human retinal organoids as a model
Cytotherapy·2025· 1 cited
Reactivating the phototransduction cascade with a mutation agnostic gene therapy preserves vision in rod-cone dystrophies
iScience·2025Open Access
Guiding G protein signaling by target enhancement of GPCRs
2025· 2 citedOpen Access
Impact of DNase digestion on titer measurements of engineered adeno-associated virus serotypes
Molecular Therapy — Methods & Clinical Development·2025· 1 citedOpen Access
Retinal organoids mirror CRISPR/Cas9 gene editing efficiency observed in vivo
2024· 1 cited
Characterization of anti-AAV2 neutralizing antibody levels in sheep prior to and following intravitreal AAV2.7m8 injection
Gene Therapy·2024· 1 citedOpen Access
Direct delivery of Cas9 or base editor protein and guide RNA complex enables genome editing in the retina
Molecular Therapy — Nucleic Acids·2024· 9 citedOpen Access
The Role of Thermal Stability in AAV Titration of Engineered Variants
2024
Peripheral Cellular Immune Responses Induced by Subretinal Adeno-Associated Virus Gene Transfer Can Be Restrained by the Subretinal-Associated Immune Inhibition Mechanism
Human Gene Therapy·2024· 6 cited
Optimal sequencing depth for measuring the concentrations of molecular barcodes
2024Open Access
AAV-Mediated Restoration of Dystrophin-Dp71 in the Brain of Dp71-Null Mice: Molecular, Cellular and Behavioral Outcomes
Cells·2024· 2 citedOpen Access
page 1 of 11Next →

Frequent Co-authors

José‐Alain Sahel(20), John G. Flannery(17), David V. Schaffer(13), Serge Picaud(11), Jens Duebel(9), Meike Visel(7), Antoine Chaffiol(7), Leah C. Byrne(6), Mélissa Desrosiers(6), Olivier Goureau(6), R. R. Klimczak(5), Kathleen D. Kolstad(5), Olivier Marre(5), William H. Merigan(4), Botond Roska(4), Céline Jaillard(4), Sacha Reichman(4), Romain Caplette(4), Elena Brazhnikova(4), Hanen Khabou(4)