K. Roger Aoki

RIKEN Nishina Center — Japan

Medicine · Health Sciences

36h-index7.2kcitations152works0.02yr avg
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Research Topics

Botulinum Toxin and Related Neurological Disorders(78), Neurological disorders and treatments(52), Hereditary Neurological Disorders(35), Pain Mechanisms and Treatments(10), Biochemical and Structural Characterization(9)

Publications152 total

Comparison of the Relative Biological Effectiveness Estimated With Two Biological Models Based on Diamond Membrane Dosimeter in Clinical Heavy Ion Cancer Therapy Field
2025
A preoperative prognostic nutritional index is a prognostic indicator in oral squamous cell carcinoma patients undergoing radical surgery
International Journal of Oral and Maxillofacial Surgery·2021· 19 cited
An Exoskeleton Upper Extremity Support for Laparoscopic Surgery : A Pilot Simulation Study
Journal of Japan Society of Computer Aided Surgery·2020· 5 citedOpen Access
Glycosphingolipid GM2 Induces Invasiveness in Irradiation-tolerant Lung Cancer Cells
Cell Structure and Function·2018· 16 citedOpen Access
Antibody responses to botulinum neurotoxin type A of toxin-treated spastic equinus children with cerebral palsy: A randomized clinical trial comparing two injection schedules
Journal of Neuroimmunology·2017· 11 cited
Submolecular recognition of the C-terminal domain of the heavy chain of botulinum neurotoxin type A by T cells from toxin-treated cervical dystonia patients
Immunobiology·2015· 5 cited
A Highly Specific Monoclonal Antibody for Botulinum Neurotoxin Type A-Cleaved SNAP25
Toxins·2015· 24 citedOpen Access
The C-Terminal Heavy-Chain Domain of Botulinum Neurotoxin A Is Not the Only Site That Binds Neurons, as the N-Terminal Heavy-Chain Domain Also Plays a Very Active Role in Toxin-Cell Binding and Interactions
Infection and Immunity·2015· 22 citedOpen Access
Regions recognized on the light chain of botulinum neurotoxin type A by T lymphocytes of SJL and BALB/c mice primed with inactivated toxin
Immunobiology·2014· 5 cited
Fusion of Golgi‐derived vesicles mediated by<scp>SNAP</scp>‐25 is essential for sympathetic neuron outgrowth but relatively insensitive to botulinum neurotoxins<i>in vitro</i>
FEBS Journal·2014· 5 citedOpen Access
Reduction of established antibody responses against botulinum neurotoxin A by synthetic monomethoxypolyethylene glycol peptide conjugates
Journal of Neuroimmunology·2014· 1 cited
Synaptotagmin II and Gangliosides Bind Independently with Botulinum Neurotoxin B but Each Restrains the Other
The Protein Journal·2014· 7 cited
The rat Digit Abduction Score (DAS) assay: A physiological model for assessing botulinum neurotoxin-induced skeletal muscle paralysis
Toxicon·2013· 52 cited
Identification of Fibroblast Growth Factor Receptor 3 (FGFR3) as a Protein Receptor for Botulinum Neurotoxin Serotype A (BoNT/A)
PLoS Pathogens·2013· 80 citedOpen Access
Location of the synaptosome binding regions on botulinum neurotoxin type B
Toxicon·2013
Identification of fibroblast growth factor receptor 3 as a protein receptor for botulinum neurotoxin serotype A
Toxicon·2013
Full genome analysis of <scp>P</scp>hilippine indigenous subgenotype <scp>IA</scp> hepatitis <scp>A</scp> virus strains from <scp>J</scp>apanese patients with imported acute hepatitis <scp>A</scp>
Hepatology Research·2013· 10 cited
Therapeutic effectiveness of botulinum neurotoxin A: Potent blockade of autonomic transmission by targeted cleavage of only the pertinent SNAP-25
Neuropharmacology·2013· 19 cited
BoNT/A Trafficking with FGFR3 in Neuronal Cell Lines Studied with Cross-Correlation RICS
Biophysical Journal·2013Open Access
Structure and Biological Activity of Botulinum Neurotoxins and Application to Cancer Therapy
Forum on Immunopathological Diseases and Therapeutics·2013
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Frequent Co-authors

J. Oliver Dolly(10), Lance E. Steward(10), M. Zouhair Atassi(8), Joseph Francis(7), Gary W. Lawrence(6), Behzod Z. Dolimbek(6), Ester Fernández‐Salas(5), Jiafu Wang(5), Joanne Wang(4), Patton E. Garay(3), M. Gilmore(3), Jianghui Meng(3), Tomas H. Zurawski(3), Ron S. Broide(3), Joseph Jankovic(3), Anton de Paiva(2), John Rubino(2), Barry M. Guyer(2), Jörg Wissel(2), Leonard A. Smith(2)