Anton de Paiva

Imperial College London — United Kingdom

Medicine · Health Sciences

10h-index1.2kcitations12works0.02yr avg
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Research Topics

Botulinum Toxin and Related Neurological Disorders(12), Neurological disorders and treatments(6), Pain Mechanisms and Treatments(3), Nerve injury and regeneration(3), Marine Toxins and Detection Methods(2)

Publications12 total

Intramuscular injection of 125I-botulinum neurotoxin-complex versus 125I-botulinum-free neurotoxin: time course of tissue distribution
Toxicon·2003· 98 cited
Functional repair of motor endplates after botulinum neurotoxin type A poisoning: Biphasic switch of synaptic activity between nerve sprouts and their parent terminals
Proceedings of the National Academy of Sciences·1999· 668 citedOpen Access
Differences in the multiple step process of inhibition of neurotransmitter release induced by tetanus toxin and botulinum neurotoxins type A and B atAplysia synapses
Neuroscience·1996· 20 cited
Expression and Purification of the Light Chain of Botulinum Neurotoxin A: A Single Mutation Abolishes Its Cleavage of SNAP-25 and Neurotoxicity after Reconstitution with the Heavy Chain
Biochemistry·1995· 52 cited
A Single Mutation in the Recombinant Light Chain of Tetanus Toxin Abolishes Its Proteolytic Activity and Removes the Toxicity Seen after Reconstitution with Native Heavy Chain
Biochemistry·1994· 64 cited
Probing the process of transmitter release with botulinum and tetanus neurotoxins
Seminars in Neuroscience·1994· 47 cited
Botulinum A Like Type B and Tetanus Toxins Fulfils Criteria for Being a Zinc‐Dependent Protease
Journal of Neurochemistry·1993· 73 cited
A role for the interchain disulfide or its participating thiols in the internalization of botulinum neurotoxin A revealed by a toxin derivative that binds to ecto-acceptors and inhibits transmitter release intracellularly.
Journal of Biological Chemistry·1993· 86 citedOpen Access
Functional Roles of Domains of Clostridial Neurotoxins: The Contribution from Studies on Aplysia
1993· 5 cited
Differences in the temperature dependencies of uptake of botulinum and tetanus toxins in Aplysia neurons
Neuroscience Letters·1992· 12 cited
Identification of domains in botulinum and tetanus toxins involved in the blockade of transmitter release in from Aplysia neurons
Neurochemistry International·1992
Light chain of botulinum neurotoxin is active in mammalian motor nerve terminals when delivered via liposomes
FEBS Letters·1990· 69 citedOpen Access

Frequent Co-authors

J. Oliver Dolly(12), Bernard Poulain(5), L Tauc(5), Patrick Foran(3), Ulrich Weller(3), K. Roger Aoki(2), Gary W. Lawrence(2), Anthony C. Ashton(2), Thomas Binz(2), Frédéric A. Meunier(1), Jordi Molgó(1), Diane Tang‐Liu(1), Tara L. Houchen(1), L. F. Chasseaud(1), Colin E. Webber(1), Clifford C. Shone(1), Giampietro Schiavo(1), Cesare Montecucco(1), Yan Li(1), Neil F. Fairweather(1)