David P. Lane

Science for Life Laboratory — Sweden

Medicine · Health Sciences

136h-index78.7kcitations958works4.62yr avg
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Research Topics

Cancer-related Molecular Pathways(428), Cancer Research and Treatments(155), Ubiquitin and proteasome pathways(99), RNA modifications and cancer(93), Monoclonal and Polyclonal Antibodies Research(89)

Publications958 total

Pharmacological activation of p53 induces dose-dependent changes in endothelial cell fate during angiogenic sprouting
Cell Death and Disease·2025Open Access
Supplementary Figure from CRISPR/Cas9-Induced DNA Damage Enriches for Mutations in a p53-Linked Interactome: Implications for CRISPR-Based Therapies
2025Open Access
Supplementary Data from CRISPR/Cas9-Induced DNA Damage Enriches for Mutations in a p53-Linked Interactome: Implications for CRISPR-Based Therapies
2025Open Access
Supplementary Data from CRISPR/Cas9-Induced DNA Damage Enriches for Mutations in a p53-Linked Interactome: Implications for CRISPR-Based Therapies
2025Open Access
Supplementary Data from CRISPR/Cas9-Induced DNA Damage Enriches for Mutations in a p53-Linked Interactome: Implications for CRISPR-Based Therapies
2025Open Access
Supplementary Table from CRISPR/Cas9-Induced DNA Damage Enriches for Mutations in a p53-Linked Interactome: Implications for CRISPR-Based Therapies
2025Open Access
Confirmation by conformation: rescue of mutant p53 in AML
Blood·2025
Editor’s Note: The MDM2/MDMX-p53 Antagonist PM2 Radiosensitizes Wild-Type p53 Tumors
Cancer Research·2025
<scp>CDK</scp> 11 inhibition induces cytoplasmic p21 <sup> <scp>WAF</scp> 1 </sup> splice variant by p53 stabilisation and <scp>SF</scp> 3 <scp>B</scp> 1 inactivation
Molecular Oncology·2025Open Access
The legacy of a gentleman scientist: Pierre Hainaut
Cell Death and Differentiation·2025Open Access
Author response for "&lt;scp&gt;CDK&lt;/scp&gt;11 inhibition induces cytoplasmic p21&lt;sup&gt;&lt;scp&gt;WAF&lt;/scp&gt;1&lt;/sup&gt; splice variant by p53 stabilisation and &lt;scp&gt;SF&lt;/scp&gt;3&lt;scp&gt;B&lt;/scp&gt;1 inactivation"
2025
Author response for "&lt;scp&gt;CDK&lt;/scp&gt;11 inhibition induces cytoplasmic p21&lt;sup&gt;&lt;scp&gt;WAF&lt;/scp&gt;1&lt;/sup&gt; splice variant by p53 stabilisation and &lt;scp&gt;SF&lt;/scp&gt;3&lt;scp&gt;B&lt;/scp&gt;1 inactivation"
2025
O-240 Automated oocyte vitrification with the DaVitri device: a prospective study on survival and blastulation
Human Reproduction·2025Open Access
Conformational modulation of intrinsically disordered transactivation domains for cancer therapy
PNAS Nexus·2025· 1 citedOpen Access
Engineered Peptide Coacervates Enable Efficient Intracellular Delivery of the MYC Inhibitor omoMYC
Molecular Pharmaceutics·2025· 5 citedOpen Access
Author Correction: Design-rules for stapled peptides with in vivo activity and their application to Mdm2/X antagonists
Nature Communications·2025Open Access
BPS2025 - Modulation of c-MYC structure and activity by targeting a conformational switch
Biophysical Journal·2025
Targeting mutant p53: Evaluation of novel anti-p53R175H monoclonal antibodies as diagnostic tools
Scientific Reports·2025· 1 citedOpen Access
The Impact of Marxist Ideas in Russia before and after the October Revolution
2024
AlphaFold with conformational sampling reveals the structural landscape of homorepeats
Structure·2024· 4 citedOpen Access
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Frequent Co-authors

Carol Midgley(6), Jiří Bártek(5), Julian Gannon(5), Sonia Laı́n(5), Jean‐Christophe Bourdon(4), Bořivoj Vojtěšek(4), Peter A. Hall(3), Richard Iggo(3), Ted R. Hupp(3), Chandra Verma(3), Ronald T. Hay(3), Arnold J. Levine(2), D M Barnes(2), R. Dover(2), Naushin Waseem(2), Alan R. Fersht(2), F Murray-Zmijewski(2), Dimitris P. Xirodimas(2), Mark K. Saville(2), Manuel S. Rodríguez(2)