Barbara J. Caldarone

Harvard University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

40h-index5.9kcitations90works2.22yr avg
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Research Topics

Receptor Mechanisms and Signaling(28), Nicotinic Acetylcholine Receptors Study(24), Neurotransmitter Receptor Influence on Behavior(14), Alzheimer's disease research and treatments(14), Neuroinflammation and Neurodegeneration Mechanisms(12)

Publications90 total

Age-dependent transcriptomic effects of morphine in the frontal cortex of female mice
Neuropharmacology·2025Open Access
A spatial atlas of the complement system uncovers unique expression patterns in postnatal brain development in mice
Nature Communications·2025Open Access
Inhibition of hippocampal mossy fiber plasticity and episodic memory by human Aβ oligomers is prevented by enhancing cAMP signaling in Alzheimer's mice
Alzheimer s & Dementia·2025· 5 citedOpen Access
Long-Term, Sex-Specific Effects of GCRsim and Gamma Irradiation on the Brains, Hearts, and Kidneys of Mice with Alzheimer’s Disease Mutations
International Journal of Molecular Sciences·2024· 2 citedOpen Access
LRP1 in GABAergic neurons is a key link between obesity and memory function
Molecular Metabolism·2024· 4 citedOpen Access
Spatial and temporal profiling of the complement system uncovered novel functions of the alternative complement pathway in brain development
2023· 4 citedOpen Access
Transplanting old organs promotes senescence in young recipients
American Journal of Transplantation·2023· 27 citedOpen Access
High-Energy, Whole-Body Proton Irradiation Differentially Alters Long-Term Brain Pathology and Behavior Dependent on Sex and Alzheimer’s Disease Mutations
International Journal of Molecular Sciences·2023· 5 citedOpen Access
GABAergic LRP1 is a key link between obesity and memory function
2022· 2 citedOpen Access
Review for "Towards a machine‐learning assisted diagnosis of psychiatric disorders and their operationalization in preclinical research: evidence from studies on addiction‐like behaviour in individual rats"
2022
Gabrb3 endothelial cell-specific knockout mice display abnormal blood flow, hypertension, and behavioral dysfunction
Scientific Reports·2022· 13 citedOpen Access
Disruption of the IL-33-ST2-AKT signaling axis impairs neurodevelopment by inhibiting microglial metabolic adaptation and phagocytic function
Immunity·2022· 162 citedOpen Access
Long-Term Sex- and Genotype-Specific Effects of 56Fe Irradiation on Wild-Type and APPswe/PS1dE9 Transgenic Mice
International Journal of Molecular Sciences·2021· 16 citedOpen Access
Peripherally administered amylin inhibits stress-like behaviors and enhances cognitive performance
Physiology & Behavior·2021· 3 cited
Author Correction: Exercise hormone irisin is a critical regulator of cognitive function
Nature Metabolism·2021· 8 citedOpen Access
Exercise hormone irisin is a critical regulator of cognitive function
Nature Metabolism·2021· 355 citedOpen Access
Focused ultrasound with anti-pGlu3 Aβ enhances efficacy in Alzheimer's disease-like mice via recruitment of peripheral immune cells
Journal of Controlled Release·2021· 35 citedOpen Access
Cis P-tau underlies vascular contribution to cognitive impairment and dementia and can be effectively targeted by immunotherapy in mice
Science Translational Medicine·2021· 65 citedOpen Access
Ultrasound-mediated blood-brain barrier disruption improves anti-pyroglutamate3 Aβ antibody efficacy and enhances phagocyte infiltration into brain in aged Alzheimer’s disease-like mice
2021Open Access
Selective 5-Hydroxytryptamine 2C Receptor Agonists Derived from the Lead Compound Tranylcypromine: Identification of Drugs with Antidepressant-Like Action
Figshare·2020Open Access
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Frequent Co-authors

Marina R. Picciotto(16), Alan P. Kozikowski(11), Sarah L. King(9), Cynthia A. Lemere(7), Paul J. Lorello(6), Allison Fedolak(6), Afshin Ghavami(6), Kevin X. Le(5), Venetia Zachariou(5), J. Brek Eaton(5), Ronald J. Lukas(5), Neil E. Paterson(5), Qiaoqiao Shi(4), Jeffrey L. Frost(4), Bryan L. Roth(4), Li-Fang Yu(4), Taleen Hanania(4), Alexia Harrist(3), Daguang Wang(3), David Lowe(3)