Yohei Mukai

Eisai (Japan) — Japan

Medicine · Health Sciences

37h-index4.0kcitations142works10.52yr avg
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Research Topics

Monoclonal and Polyclonal Antibodies Research(34), RNA Interference and Gene Delivery(26), Immunotherapy and Immune Responses(24), Virus-based gene therapy research(20), Glycosylation and Glycoproteins Research(13)

Publications142 total

Evaluating the impact of lyophilization process parameters on mRNA encapsulated lipid nanoparticles using machine learning
Journal of Drug Delivery Science and Technology·2025
Delivery of a BET protein degrader via a CEACAM6-targeted antibody–drug conjugate inhibits tumour growth in pancreatic cancer models
Nature Communications·2024· 21 citedOpen Access
Accumulation of annexin A2 and S100A10 prevents apoptosis of apically delaminated, transformed epithelial cells
Proceedings of the National Academy of Sciences·2023· 15 citedOpen Access
DOCK8-expressing T follicular helper cells newly generated beyond self-organized criticality cause systemic lupus erythematosus
iScience·2021· 8 citedOpen Access
The CD44/COL17A1 pathway promotes the formation of multilayered, transformed epithelia
Current Biology·2021· 58 citedOpen Access
Newly Generated DOCK8-Expressing T Follicular Helper Cells Cause Systemic Lupus Erythematosus
SSRN Electronic Journal·2021Open Access
A Newly Generated DOCK8-expressing T Follicular Helper Cell Type, aiCD4 T Cell, Causes Systemic Lupus Erythematosus: Self-Organized Criticality Theory
Research Square (Research Square)·2020Open Access
A trimeric structural fusion of an antagonistic tumor necrosis factor-α mutant enhances molecular stability and enables facile modification
Journal of Biological Chemistry·2017· 16 citedOpen Access
Distribution of Silver Nanoparticles to Breast Milk and Their Biological Effects on Breast-Fed Offspring Mice
ACS Nano·2016· 69 cited
Metal nanoparticles in the presence of lipopolysaccharides trigger the onset of metal allergy in mice
Nature Nanotechnology·2016· 67 cited
A Novel Bispecific Antibody against Human CD3 and Ephrin Receptor A10 for Breast Cancer Therapy
PLoS ONE·2015· 44 citedOpen Access
Abstract 4377: Biodistribution and therapeutic effects of a monoclonal antibody against Eph receptor A10 in a breast cancer xenograft model
Cancer Research·2015
Identification and evaluation of metastasis-related proteins, oxysterol binding protein-like 5 and calumenin, in lung tumors
International Journal of Oncology·2015· 58 citedOpen Access
Aminopeptidase P3 (APP3), a novel member of the TNF/TNFR2 signaling complex, induces phosphorylation of JNK
Journal of Cell Science·2015· 22 citedOpen Access
Structural Basis for Signal Initiation by TNF and TNFR
2015
Generation and characterization of a bispecific diabody targeting both EPH receptor A10 and CD3
Biochemical and Biophysical Research Communications·2014· 22 cited
Size and surface modification of amorphous silica particles determine their effects on the activity of human CYP3A4 in vitro
Nanoscale Research Letters·2014· 15 citedOpen Access
Evaluation of silica nanoparticle binding to major human blood proteins
Nanoscale Research Letters·2014· 29 citedOpen Access
Intestinal absorption and biological effects of orally administered amorphous silica particles
Nanoscale Research Letters·2014· 52 citedOpen Access
788: Expression of Annexin A4 regulates cisplatin-susceptibility in malignant mesothelioma
European Journal of Cancer·2014
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Frequent Co-authors

Shinsaku Nakagawa(39), Yasuo Tsutsumi(35), Shin‐ichi Tsunoda(27), Haruhiko Kamada(25), Yasuo Yoshioka(22), Yasuo Yoshioka(21), Naoki Okada(20), Hiroko Shibata(15), Yasuhiro Abe(15), Kazuya Nagano(15), Tadanori Mayumi(14), Tomoaki Yoshikawa(11), Takayuki Okamoto(10), Kazuma Higashisaka(8), Tomohiro Morishige(7), Madoka Taniai(7), Tetsuya Nomura(7), Xinglei Yao(6), Kazuhiko Matsuo(6), Sunao Imai(6)