Grace A. Wells

San Diego State University — United States

Medicine · Health Sciences

3h-index40citations10works0.52yr avg
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Research Topics

Glioma Diagnosis and Treatment(5), Cancer, Hypoxia, and Metabolism(5), Epigenetics and DNA Methylation(3), Cancer Genomics and Diagnostics(3), Mosquito-borne diseases and control(2)

Publications10 total

Catalytically distinct metabolic enzyme isocitrate dehydrogenase 1 mutants tune phenotype severity in tumor models
Journal of Biological Chemistry·2025· 1 citedOpen Access
Catalytically distinct IDH1 mutants tune phenotype severity in tumor models
2024Open Access
Abstract C036: Investigating the phenotypic changes in <i>in vitro</i> and <i>in vivo</i> cancer models expressing isocitrate dehydrogenase 1 (IDH1) mutations R132H and R132Q
Cancer Epidemiology Biomarkers & Prevention·2023
The Catalytic Features of IDH1 Mutations Can Drive Neomorphic Activity, Phenotype Severity, and Inhibitor Binding
The FASEB Journal·2020
Abstract 4381: Investigating the reversible MDH1 catalytic reaction in squamous non-small cell lung cancer
Cancer Research·2019
Activity of Selected Nucleoside Analogue ProTides against Zika Virus in Human Neural Stem Cells
Viruses·2019· 15 citedOpen Access
Activity of Selected Nucleoside Analogue ProTides against Zika Virus in Human Neural Stem Cells
2019· 7 citedOpen Access
Inhibitor potency varies widely among tumor-relevant human isocitrate dehydrogenase 1 mutants
Biochemical Journal·2018· 15 cited
Understanding the Structure‐Function Relationship of IDH1 R132 mutants and the Effect of Allosteric Inhibitors
The FASEB Journal·2018
Assay and Subcellular Localization of Adenosine Diphosphatase in Human Neutrophil Polymorphonuclear Leucocytes
Clinical Science·1979· 2 cited

Frequent Co-authors

Christal D. Sohl(9), Lucas A. Luna(4), An Hoang(4), Diego Avellaneda Matteo(3), David A. Scott(3), Jamie M. Schiffer(3), Mikella Robinson(3), Mowaffaq Adam Ahmed Adam(3), Joi Weeks(3), Giovanni Quichocho(3), Carrie D. House(3), Jean Bernatchez(2), Michael Coste(2), Sungjun Beck(2), Alex E. Clark(2), Zhe Zhu(2), Byron W. Purse(2), Jair L. Siqueira-Neto(2), Adam Grunseth(2), Olga Zagnitko(2)