Lior Pachter

California Institute of Technology — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

82h-index108.8kcitations425works7.82yr avg
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Research Topics

Genomics and Phylogenetic Studies(118), Single-cell and spatial transcriptomics(105), RNA and protein synthesis mechanisms(66), RNA Research and Splicing(64), RNA modifications and cancer(52)

Publications415 total

Computational array reconstruction with accumap for spatial transcriptomics
2025Open Access
Uniform pre-processing of bacterial single-cell RNA-seq
2025Open Access
Long-read sequencing transcriptome quantification with lr-kallisto
PLoS Computational Biology·2025· 2 citedOpen Access
<i>k</i> -spaces: Mixtures of Gaussian latent variable models
2025Open Access
Determining gene specificity from multivariate single-cell RNA sequencing data
2025Open Access
Biophysical constraints on mRNA decay rates shape macroevolutionary divergence in steady-state abundances
2025Open Access
Analogies between the virial theorem and the Price equation
Physical review. E·2025
The Rayleigh Quotient and Contrastive Principal Component Analysis I
2025Open Access
Joint Biophysical Modeling of Paired Single-Cell RNA and Protein Measurements
2025· 1 citedOpen Access
Monod: model-based discovery and integration through fitting stochastic transcriptional dynamics to single-cell sequencing data
Nature Methods·2025· 4 cited
CTIM-07. A PHASE 1 STUDY OF INTRAVENTRICULARLY ADMINISTERED AUTOLOGOUS HER2-TARGETING CHIMERIC ANTIGEN RECEPTOR T CELLS (HER2-CAR T CELLS), WITH AND WITHOUT LYMPHODEPLETION, IN HER2-POSITIVE BREAST CANCER PATIENTS WITH RECURRENT BRAIN AND/OR LEPTOMENINGEAL METASTASES
Neuro-Oncology·2025Open Access
The Biodiversity Cell Atlas: mapping the tree of life at cellular resolution
Nature·2025· 3 cited
Reference-based variant detection with varseek
2025Open Access
A plea for academic truth
Journal of Comparative Physiology A·2025· 4 cited
Transcriptomic responses to endurance exercise training in rats
2025Open Access
Pseudoassembly of k-mers
2025· 1 citedOpen Access
Extrinsic biological stochasticity and technical noise normalization of single-cell RNA sequencing data
2025· 1 citedOpen Access
Systematic cell-type resolved transcriptomes of 8 tissues in 8 lab and wild-derived mouse strains captures global and local expression variation
2025· 4 citedOpen Access
Resilience of A Learned Motor Behavior After Chronic Disruption of Inhibitory Circuits
2025Open Access
Resilience of A Learned Motor Behavior After Chronic Disruption of Inhibitory Circuits
2025· 1 citedOpen Access
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Frequent Co-authors

Cole Trapnell(9), Nicolas Bray(8), Harold Pimentel(7), Edward M. Rubin(6), Inna Dubchak(6), Colin N. Dewey(6), Adam Roberts(5), Páll Melsted(5), Valentine Svensson(4), Steven L. Salzberg(3), John L. Rinn(3), Kelly A. Frazer(3), Eduardo da Veiga Beltrame(3), Michael B. Eisen(3), Hongkui Zeng(3), Zizhen Yao(3), Olivia Fong(3), Thuc Nghi Nguyen(3), Kimberly A. Smith(3), Bosiljka Tasic(3)