Viacheslav V. Trush

Biochemistry, Genetics and Molecular Biology · Life Sciences

9h-index242citations20works0.02yr avg
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Research Topics

Protein Tyrosine Phosphatases(9), Epigenetics and DNA Methylation(5), Cancer-related gene regulation(5), ATP Synthase and ATPases Research(4), Bioactive Compounds and Antitumor Agents(3)

Publications20 total

THE CORRECTION BY ARGININE, MODERATE PHYSICAL ACTIVITY AND THEIR COMBINATION OF SKELETAL MUSCLE CONTRACTIVE FUNCTION DISTURBANCES` FOR STEROID MYOPATHY IN EXPERIMENTS ON RATS
Scientific Notes of V I Vernadsky Crimean Federal University Biology Chemistry·2024
Enzymatic nucleosome acetylation selectively affects activity of histone methyltransferases in vitro
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms·2022· 12 cited
Discovery of small molecule antagonists of human Retinoblastoma Binding Protein 4 (RBBP4)
2022· 1 citedOpen Access
Discovery of the SMYD3 Inhibitor BAY-6035 Using Thermal Shift Assay (TSA)-Based High-Throughput Screening
SLAS DISCOVERY·2021· 25 citedOpen Access
A First-in-Class, Highly Selective and Cell-Active Allosteric Inhibitor of Protein Arginine Methyltransferase 6
Journal of Medicinal Chemistry·2021· 25 citedOpen Access
CCDC 1824030: Experimental Crystal Structure Determination
The Cambridge Structural Database·2019Open Access
CCDC 1824034: Experimental Crystal Structure Determination
The Cambridge Structural Database·2019Open Access
Selective, Small-Molecule Co-Factor Binding Site Inhibition of a Su(var)3–9, Enhancer of Zeste, Trithorax Domain Containing Lysine Methyltransferase
Journal of Medicinal Chemistry·2019· 19 citedOpen Access
Calixarene-based phosphinic acids as inhibitors of protein tyrosine phosphatases
Bioorganic & Medicinal Chemistry Letters·2019· 25 citedOpen Access
The assessment of sulfonylcalix[4]arene derivatives as inhibitors of protein tyrosine phosphatases
Journal of organic and pharmaceutical chemistry·2018· 2 citedOpen Access
Abstract 1646: Discovery and characterization of BAY-6035, a novel benzodiazepine-based SMYD3 inhibitor
Cancer Research·2018· 2 cited
Targeting Human Retinoblastoma Binding Protein 4 (RBBP4) and 7 (RBBP7)
2018· 7 citedOpen Access
Sulfonyl-bridged Calix[4]arene as an Inhibitor of Protein Tyrosine Phosphatases
French-Ukrainian Journal of Chemistry·2017· 5 citedOpen Access
Inhibitory potential of polyhydroxylated fullerenes against protein tyrosine phosphatase 1B
The Ukrainian Biochemical Journal·2015· 1 citedOpen Access
Polycarboxylic fullerene derivatives as protein tyrosine phosphatase inhibitors
Mendeleev Communications·2015· 14 cited
Evaluation of inhibition of protein tyrosine phosphatase 1B by calixarene-based α-ketophosphonic acids
Chemical Biology Letters·2015· 6 citedOpen Access
Phosphonate monoesters on a thiacalix[4]arene framework as potential inhibitors of protein tyrosine phosphatase 1B
Organic & Biomolecular Chemistry·2015· 20 cited
Fullerene derivatives as a new class of inhibitors of protein tyrosine phosphatases
Bioorganic & Medicinal Chemistry Letters·2014· 28 cited
Calix[4]arene α-hydroxymethylphosphonic acids as potential inhibitors of protein tyrosine phosphatases
Journal of organic and pharmaceutical chemistry·2014· 6 citedOpen Access
Calix[4]arene methylenebisphosphonic acids as inhibitors of protein tyrosine phosphatase 1B
Bioorganic & Medicinal Chemistry Letters·2013· 44 citedOpen Access

Frequent Co-authors

Andriy I. Vovk(10), Masoud Vedadi(8), C.H. Arrowsmith(8), Vsevolod Yu. Tanchuk(7), Vitaly I. Kаlchеnkо(7), Dalia Baršytė-Lovejoy(7), Peter J. Brown(7), Oleksandr Kobzar(6), Fengling Li(6), Sidney H. Kennedy(5), Aiping Dong(5), Matthieu Schapira(5), Hong Zeng(4), S. О. Cherenok(3), Megha Abbey(3), Irene Chau(3), Vladyslav M. Buldenko(3), A. B. Drapailo(3), Magdalena M. Szewczyk(3), Alexandria P. Taylor(3)